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http://dx.doi.org/10.1007/s10620-024-08675-4 | DOI Listing |
Cochrane Database Syst Rev
September 2025
Division of Gastroenterology, Hepatology, and Nutrition, SickKids Research Institute and SickKids Learning Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Background: Training in endoscopy has traditionally been based upon an apprenticeship model, where novices develop their skills on real patients under the supervision of experienced endoscopists. In an effort to prioritise patient safety, simulation training has emerged as a means to allow novices to practice in a risk-free environment. This is the second update of the review, which was first published in 2012 and updated in 2018.
View Article and Find Full Text PDFLife (Basel)
June 2025
General and Esophageal Surgery Clinic, Sfanta Maria Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Goblet cell adenocarcinomas (GCAs) are an exceedingly rare subtype of tumors, almost exclusively occurring in the appendix, and characterized by features overlapping both adenocarcinomas and neuroendocrine tumors (NETs), which has historically led to confusion and varied nomenclature. This study presents a comprehensive review of the literature highlighting particularities of this type of malignancy, starting from a rare case of a 54-year-old female operated on in our clinic for an appendiceal tumor, initially suspected to be a mucinous neoplasm based on colonoscopic biopsy, which was ultimately confirmed to be goblet cell adenocarcinoma on both intraoperative frozen section and definitive pathological examination. Exhibiting signs and symptoms associated with an abdominal mass, she underwent a right hemicolectomy with partial omentectomy for locally advanced, high-grade, invasive goblet cell adenocarcinoma of the appendix with lymphatic macro metastases and epiploic invasion, categorized as AJCC stage IVb carcinomatosis.
View Article and Find Full Text PDFBiomed Opt Express
June 2025
KIOS Research and Innovation Center of Excellence, Department of Electrical and Computer Engineering, University of Cyprus, Nicosia, Cyprus.
Colorectal cancer (CRC) is the second leading cause of cancer-related morbidity and mortality in both men and women globally. CRC predominantly arises from dysplastic polyps that, over time, progressively evolve into malignancies. Population-wide screening through colonoscopy remains the cornerstone of CRC prevention.
View Article and Find Full Text PDFWorld J Gastrointest Surg
June 2025
Endoscopy Center, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China.
Background: Colonoscopic polypectomy is a crucial procedure for the prevention and treatment of colorectal cancer, with its success and safety largely dependent on the quality of bowel preparation. Currently, polyethylene glycol electrolyte solution remains the standard method for bowel preparation, but its use may cause patient discomfort and incomplete cleansing.
Aim: To evaluate impact of enhanced and conventional bowel preparation protocols on the outcomes of colonoscopic polypectomy.
Am J Gastroenterol
June 2025
Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China .
Introduction: The sigmoid colon is the most tortuous part of the large intestine and is often the most easily compressed during intubation and more easily missed during withdrawal observation. This study aimed to ascertain whether a second sigmoid colon intubation could enhance the adenoma detection rate (ADR).
Methods: We conducted a randomized controlled trial of patients 45 years and older with a body mass index over 24 who underwent colonoscopy.