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Article Abstract
An efficient redox-neutral palladium-catalyzed system has been developed to introduce indole and pyrrole units to a wide range of bioactive molecules late-stage aryl C-H activation, providing a robust tool for medicinal chemists to explore structure-activity relationships (SARs). Furthermore, the successful gram-scale reaction and subsequent synthetic investigations demonstrate the potential application of this established method in organic synthesis, materials science, and biochemistry.
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