Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ppul.27339 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Porcine respiratory disease complex induces pulmonary fibrosis related to the aberrant sphingolipid metabolism.
Int J Exp Pathol
September 2025
Laboratory of Pharmacobiology, State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Porcine respiratory disease complex (PRDC) is a common syndrome in the modern swine industry worldwide, and its pathogenesis remains unclear to date. Our study aimed to investigate PRDC-induced pulmonary fibrosis and sphingolipid metabolism, and their relationship. Mouse and cell line (A549 and 3D4/21) models exposed to bleomycin and/or transforming growth factor-β1 (TGF-β1) were developed.
View Article and Find Full Text PDFLCCPs exposure induces pulmonary inflammatory injury via AIM2 mediated pulmonary macrophage PANoptosis and M1 polarization.
Environ Pollut
August 2025
College of Animal Science and Technology, Jilin Agricultural University, Changchun, 130118, China. Electronic address:
In recent years, with the wide application of long-chain chlorinated paraffins (LCCPs), long-chain chlorinated paraffins have been detected all over the world. High concentrations of LCCPs are being detected in the air of human living environments. As the main gas exchange organ of the human body, the lungs are responsible for transporting oxygen throughout the body, but there are no studies on the toxicological effects of LCCPs on the lungs.
View Article and Find Full Text PDFMathematical modelling of the heterogeneity of disease progression and treatment outcomes in patients with COVID-19.
Front Microbiol
July 2025
Department of Mathematics, College of Sciences, Sichuan Agricultural University, Ya'an, China.
Pneumonia caused by SARS-CoV-2 infection is a self-limiting disease. Its progression and prognosis are highly heterogeneous among people of different ages, genders, and living with different life styles. Such heterogeneity also exists in treatment outcomes of different patients.
View Article and Find Full Text PDFAda2 acts upstream of Pdr802 in regulating macrophage-enhanced virulence of .
Microbiol Spectr
September 2025
Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
is the leading cause of fungal meningitis in humans and a major source of mortality in people living with HIV. Infection starts in the lungs and results in meningoencephalitis after dissemination via the bloodstream. Alveolar macrophages are the first immune cells to encounter the infection and are usually capable of clearing it.
View Article and Find Full Text PDFUpdate of the International Multidisciplinary Classification of the Interstitial Pneumonias: An ERS/ATS Statement.
Eur Respir J
August 2025
Department of Histopathology, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, and National Heart and Lung Institute, Imperial College London, UK.
Article Synopsis
- The 2013 classification of idiopathic interstitial pneumonia has been updated to include secondary causes and new subcategories.
- A committee of experts developed this new classification through consensus, focusing on important advances in the field.
- Key updates include changes in terminology, subclassification of disorders, and consideration of diagnostic confidence, along with a discussion on future research needs.