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Purpose Postoperative pain management methods for tonsillectomy commonly include the use of opioids, non-steroidal anti-inflammatory drugs, and acetaminophen. However, some patients report pain despite the use of these medications. In recent years, ultrasound-guided selective glossopharyngeal nerve block (UGSGNB) and ultrasound-guided maxillary nerve block (UGMNB) have been reported to be effective for analgesia post-tonsillectomy. We retrospectively analyzed the effects of UGSGNB and UGMNB in the perioperative management of patients who underwent tonsillectomy under general anesthesia. Methods This retrospective study evaluated adults (18-61 years old) who had received general anesthesia for tonsillectomy. The control group comprised 25 patients who received general anesthesia using the standard protocol, and the nerve block group comprised 10 patients who also received additional UGGNB and UGMNB. Results While these nerve blocks may have contributed to improving the postoperative food intake, they did not reduce the frequency of postoperative analgesia used. Improved dietary intake after UGSGNB and UGMNB could be advantageous for postoperative recovery. Conclusion Further research with a larger number of cases and prospective intervention studies are necessary to determine the effects of combining UGSGNB and UGMNB for post-tonsillectomy analgesia.
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http://dx.doi.org/10.7759/cureus.68672 | DOI Listing |
Paediatr Anaesth
October 2025
Human Anatomy and Embryology Unit, Faculty of Medicine and Health Sciences, Universitat of Barcelona, Barcelona, Spain.
The costoclavicular brachial plexus block has gained relevance as a safe and effective regional anesthesia technique for upper limb orthopedic surgery in adults, but data in pediatric populations remain limited. This study aimed to evaluate the incidence of phrenic nerve palsy associated with CBPB in pediatric patients. We conducted a descriptive observational study in 30 children undergoing upper limb orthopedic surgery.
View Article and Find Full Text PDFNeural Plast
September 2025
Department of Anesthesiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Astrocytes play a crucial role in ensuring neuronal survival and function. In stroke, astrocytes trigger the unfolded protein response (UPR) to restore endoplasmic reticulum homeostasis. Mesencephalic astrocyte-derived neurotrophic factor (MANF), a newly identified endoplasmic reticulum stress-induced neurotrophic factor, attenuates cerebral ischemic injury by reducing inflammatory responses.
View Article and Find Full Text PDFDrug Des Devel Ther
September 2025
Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
Purpose: This study aimed to compare the analgesic efficacy of liposomal bupivacaine with that of traditional ropivacaine in adductor canal blocks for patients undergoing knee arthroplasty.
Patients And Methods: A total of 119 consenting participants, who were scheduled for elective knee arthroplasty (including total knee replacement and unicompartmental knee replacement) under general anesthesia, were randomly assigned to either receive an ultrasound-guided adductor canal block with ropivacaine or liposomal bupivacaine. The primary endpoint of this study was the pain scores at 2, 24, 48, and 72 hours post-surgery.
Cureus
August 2025
Anesthesiology, Asahi General Hospital, Asahi, JPN.
Awake tracheal intubation (ATI) is a crucial technique for difficult airway management, particularly in patients with obesity, restricted neck movement, or upper airway abnormalities. Despite its efficacy, ATI is often avoided because of the technical challenges and stress it imposes on patients and anesthesiologists. We describe a new method, termed "intubation maintaining spontaneous breathing with three nerve blocks technique" (3N technique), which leverages nerve blocks to suppress reflexes, preserve spontaneous breathing, and facilitate smooth intubation.
View Article and Find Full Text PDFOpen Med (Wars)
August 2025
Department of Pain, Shanghai Pudong New Area People's Hospital, Shanghai, 200000, China.
Objective: This study examines the efficacy of ultrasound (US)-guided paravertebral nerve block (PVB) with and without MRI fusion for chronic back pain management.
Methods: A retrospective analysis of 20 patients, split into US-MRI fusion-guided (IF group, = 10) and traditional US-guided (U group, = 10) PVB, was conducted. Pain intensity, gabapentin dosage, procedure duration, and treatment efficacy were compared using numerical rating scale (NRS) scores.