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Objective: The current study sought to clarify and harness the incremental validity of emotional dysregulation and unawareness (EDU) in emerging adulthood, beyond ADHD symptoms and with respect to concurrent classification of impairment and co-occurring problems, using machine learning techniques.
Method: Participants were 1,539 college students ( = 19.5, 69% female) with self-reported ADHD diagnoses from a multisite study who completed questionnaires assessing ADHD symptoms, EDU, and co-occurring problems.
Results: Random forest analyses suggested EDU dimensions significantly improved model performance (s < .001) in classifying participants with impairment and internalizing problems versus those without, with the resulting ADHD + EDU classification model demonstrating acceptable to excellent performance (except in classification of Work Impairment) in a distinct sample. Variable importance analyses suggested inattention sum scores and the Limited Access to Emotional Regulation Strategies EDU dimension as the most important features for facilitating model classification.
Conclusion: Results provided support for EDU as a key deficit in those with ADHD that, when present, helps explain ADHD's co-occurrence with impairment and internalizing problems. Continued application of machine learning techniques may facilitate actuarial classification of ADHD-related outcomes while also incorporating multiple measures.
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http://dx.doi.org/10.1177/10870547241284829 | DOI Listing |
J Interpers Violence
September 2025
University of Memphis, TN, USA.
Complex trauma (CT), or chronic interpersonal trauma that begins early in life, has been associated with a multitude of negative outcomes, including posttraumatic stress symptoms (PTSS) and emotion dysregulation. Some CT survivors also exhibit adaptive functioning, such as resilience. Social and contextual factors may have an impact on the expression of adverse and adaptive outcomes for CT survivors, yet have been neglected.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Background: Peripartum depression (PPD) is a form of major depressive disorder (MDD) that begins during the peripartum period and poses a significant mental health challenge affecting 10 to 29% of women.
Objective: This systematic review and multimodal activation likelihood estimation (ALE) meta-analysis explored the distinct structural, functional, and metabolic features of the PPD brain as compared to female non-peripartum MDD.
Methods: For this purpose, we conducted a comprehensive literature search in PubMed, Embase and PsycINFO databases to identify peer-reviewed original studies investigating the neural correlates associated with PPD or fMDD.
J Affect Disord
September 2025
SCP Psychiatry, 1170 Pontiac Avenue, Cranston, RI, 02920, United States.
Background: Emotion dysregulation and social functioning are important predictors of depression severity. It remains unclear whether these factors independently or interactively contribute to depression severity amongst psychiatric patients with depressive disorders.
Method: 340 psychiatric outpatients with a principal depressive disorder were interviewed using the Structured Clinical Interview for DSM-IV (SCID).
J Affect Disord
September 2025
Department of Psychiatry, Strasbourg University Hospitals, France; Faculty of Medicine, Maieutic and Health Sciences, University of Strasbourg, France; INSERM UMR_S 1329, Team Psychiatry, Department of Psychiatry, Strasbourg, France. Electronic address:
Introduction: Emotion dysregulation is common in many different psychiatric disorders and it can be effectively treated with the well-established Dialectical Behavioral Therapy (DBT). Despite its clinical relevance and increasing scientific interest, emotional dysregulation (ED) is sometimes conflated with emotional lability (EL). However, these constructs differ: ED involves top-down neurobiological processes, while EL involves bottom-up processes.
View Article and Find Full Text PDFJ Affect Disord
September 2025
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy; Department of Neuroscience, University of Pisa Hospital, Pisa, Italy.
Emotion dysregulation (ED), a core feature of Bipolar Disorder (BD), contributes to symptom severity, mood instability, and reduced quality of life. Emerging evidence suggests that interoception-the ability to perceive and integrate internal bodily signals-may play a pivotal role in shaping emotional experience. However, the relationship between interoceptive sensibility and ED in BD remains poorly understood.
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