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Background: Emotion dysregulation and social functioning are important predictors of depression severity. It remains unclear whether these factors independently or interactively contribute to depression severity amongst psychiatric patients with depressive disorders.
Method: 340 psychiatric outpatients with a principal depressive disorder were interviewed using the Structured Clinical Interview for DSM-IV (SCID). Participants' social functioning and depression severity were rated during the SCID evaluation, and emotion dysregulation was assessed concurrently using the Difficulties in Emotion Regulation Scale (DERS). Hierarchical regression analyses examined the independent and interactive effects of social functioning and emotion dysregulation on depression severity.
Results: Emotion dysregulation (b = 0.13, SE = 0.04, p = .003) was significantly associated with greater depression severity. Social functioning (b = 2.10, SE = 1.19, p = .078) and its interaction with emotion dysregulation (b = -0.01, SE = 0.01, p = .265) were not significant predictors. These findings indicate that the effect of social functioning on depression severity was not robust when controlling for emotion dysregulation and their interaction, and that emotion dysregulation did not moderate the relationship between social functioning and depression severity.
Conclusion: Emotion dysregulation plays a robust, independent role in predicting depression severity, even when accounting for social functioning and demographic covariates. This study contributes to the growing literature on the intersection of emotion dysregulation and social functioning in depression and extends this work to a clinically diagnosed sample. Future research should examine how changes in these variables during treatment relate to symptom improvement.
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http://dx.doi.org/10.1016/j.jad.2025.120191 | DOI Listing |
Psychol Sci
September 2025
School of Educational Psychology and Counselling, Faculty of Education, Monash University.
This study examined the sequence and timing of sexual identity development (SID) milestones among Generation Z LGBTQ+ Australians, focusing on variations across subgroups and their relationship with minority stressors. The study included 490 Australian LGBTQ+ individuals aged 16 to 26, predominantly White ( = 389) and assigned female at birth ( = 402), with a balanced distribution between cisgender and gender-diverse participants. Demographic differences in the timing and achievement of SID milestones were found for sexual and gender identity.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Neurobiology of Stress Research Group, Szentágothai Research Centre, University of Pécs, Pécs, Hungary.
Background: Previous studies indicate that hippocampal (subfield) and amygdala volumes may correlate with specific cognitive functions, coping strategies and emotion regulation. Here, we investigated associations between emotional processing and volumes of hippocampal subfields and amygdala. We focused on depressed patients since emotional dysregulation and hippocampal volume shrinkage are characteristic of them.
View Article and Find Full Text PDFJ Interpers Violence
September 2025
University of Memphis, TN, USA.
Complex trauma (CT), or chronic interpersonal trauma that begins early in life, has been associated with a multitude of negative outcomes, including posttraumatic stress symptoms (PTSS) and emotion dysregulation. Some CT survivors also exhibit adaptive functioning, such as resilience. Social and contextual factors may have an impact on the expression of adverse and adaptive outcomes for CT survivors, yet have been neglected.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Background: Peripartum depression (PPD) is a form of major depressive disorder (MDD) that begins during the peripartum period and poses a significant mental health challenge affecting 10 to 29% of women.
Objective: This systematic review and multimodal activation likelihood estimation (ALE) meta-analysis explored the distinct structural, functional, and metabolic features of the PPD brain as compared to female non-peripartum MDD.
Methods: For this purpose, we conducted a comprehensive literature search in PubMed, Embase and PsycINFO databases to identify peer-reviewed original studies investigating the neural correlates associated with PPD or fMDD.
J Affect Disord
September 2025
SCP Psychiatry, 1170 Pontiac Avenue, Cranston, RI, 02920, United States. Electronic address:
Background: Emotion dysregulation and social functioning are important predictors of depression severity. It remains unclear whether these factors independently or interactively contribute to depression severity amongst psychiatric patients with depressive disorders.
Method: 340 psychiatric outpatients with a principal depressive disorder were interviewed using the Structured Clinical Interview for DSM-IV (SCID).