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The automatic recognition and quantitative analysis of abnormal behavior in mice play a crucial role in behavioral observation experiments in neuroscience, pharmacology, and toxicology. Due to the challenging definition of abnormal behavior and difficulty in collecting training samples, directly applying behavior recognition methods to identify abnormal behavior is often infeasible. This paper proposes ABNet, an AI-empowered abnormal action recognition approach for mice. ABNet utilizes an enhanced Spatio-Temporal Graph Convolutional Network (ST-GCN) as an encoder; ST-GCN combines graph convolution and temporal convolution to efficiently capture and analyze spatio-temporal dynamic features in graph-structured data, making it suitable for complex tasks such as action recognition and traffic prediction. ABNet trains the encoding network with normal behavior samples, then employs unsupervised clustering to identify abnormal behavior in mice. Compared to the original ST-GCN network, the method significantly enhances the capabilities of feature extraction and encoding. We conduct comprehensive experiments on the Kinetics-Skeleton dataset and the mouse behavior dataset to evaluate and validate the performance of ABNet in behavior recognition and abnormal motion detection. In the behavior recognition experiments conducted on the Kinetics-Skeleton dataset, ABNet achieves an accuracy of 32.7% for the top one and 55.2% for the top five. Moreover, in the abnormal behavior analysis experiments conducted on the mouse behavior dataset, ABNet achieves an average accuracy of 83.1%.
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http://dx.doi.org/10.3390/bioengineering11090930 | DOI Listing |
JMIR Res Protoc
September 2025
Department of Urology, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Background: Circumcision is a widely practiced procedure with cultural and medical significance. However, certain penile abnormalities-such as hypospadias or webbed penis-may contraindicate the procedure and require specialized care. In low-resource settings, limited access to pediatric urologists often leads to missed or delayed diagnoses.
View Article and Find Full Text PDFBraz Oral Res
September 2025
Universidade Estadual Paulista - Unesp, Araçatuba School of Dentistry, Department of Basic Science, Araçatuba, SP, Brazil.
The purpose of our review was to group the evidence and attempt to provide a consensus on the behavior of salivary flow rate in patients with Down syndrome. Observational studies evaluating salivary flow rate in children and teenagers with Down syndrome compared with non-syndrome individuals were selected. Ten sources of information were researched.
View Article and Find Full Text PDFSci Prog
September 2025
Shenzhen University Sixth Affiliated Hospital, Shenzhen Nanshan People's Hospital, Shenzhen, China.
Colorectal cancer ranks among the most prevalent and lethal malignant tumors globally. Historically, the incidence of colorectal cancer in China has been lower than that in developed European and American countries; however, recent trends indicate a rising incidence due to changes in dietary patterns and lifestyle. Lipids serve critical roles in human physiology, such as energy provision, cell membrane formation, signaling molecule function, and hormone synthesis.
View Article and Find Full Text PDFJ Magn Reson Imaging
September 2025
School of Biomedical Engineering, Guangdong Provincial Key Laboratory of Medical Image Processing and Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China.
Background: The dynamic progression of gray matter (GM) microstructural alterations following radiotherapy (RT) in patients, and the relationship between these microstructural abnormalities and cortical morphometric changes remains unclear.
Purpose: To longitudinally characterize RT-related GM microstructural changes and assess their potential causal links with classic morphometric alterations in patients with nasopharyngeal carcinoma (NPC).
Study Type: Prospective, longitudinal.
HLA
September 2025
Aix Marseille Univ, CNRS, EFS, ADES, Marseille, France.
Abnormal expression of HLA class Ib, MICA and MICB molecules is associated with the evolution of pathological conditions and clinical settings. Here, we use RNA-sequencing data from two publicly-available projects, from different human organs and tissues and at single-cell level, to present their transcriptional expression throughout the human body, in comparison to that of HLA class Ia, HLA class II, their costimulatory molecules, and the main HLA transcription factors. Our analyses for 21 target genes reveal that median gene expression differs by orders of magnitude and that the classical/non-classical HLA distinction is not absolute for overall expression.
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