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The increasing prevalence of screen time among modern citizens has raised concerns regarding its potential impact on neuroinflammation and overall brain health. This review examines the complex interconnections between screen time and neuroinflammatory processes, particularly in children and adolescents. We analyze existing literature that explores how excessive digital media use can lead to alterations in neurobiological pathways, potentially exacerbating inflammatory responses in the brain. Key findings suggest that prolonged exposure to screens may contribute to neuroinflammation through mechanisms such as disrupted sleep patterns, diminished cognitive engagement, and increased stress levels. Similarly, we discuss the implications of these findings for mental health and cognitive development, emphasizing the need for a balanced approach to screen time. This review highlights the necessity for further research to elucidate the causal relationships and underlying mechanisms linking screen time and neuroinflammation, thereby informing guidelines for healthy media consumption.
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http://dx.doi.org/10.1007/s11010-024-05123-9 | DOI Listing |
Front Psychol
August 2025
Department of Educational Psychology and Pedagogy, Faculty of Psychology, Lomonosov Moscow State University, Moscow, Russia.
Family socioeconomic status is broadly acknowledged to be associated with child development and wellbeing. However, the extent of this association across various dimensions of child development remains a topic of ongoing debate. This study aims to investigate the relationship between parental education and child cognitive and socioemotional skills, as well as the mediating role of children's leisure time activities, including screen time and shared book reading.
View Article and Find Full Text PDFFront Pharmacol
August 2025
General Surgery Department Three, Gansu Province Central Hospital, Lanzhou, China.
Fast and early detection of low-dose chemical toxicity is a critical unmet need in toxicology and human health, as conventional 2D culture models often fail to capture subtle cellular responses induced by sub-toxic exposures. Here, we present a bioengineered three-dimensional (3D) electrospun nanofibrous scaffold composed of polycaprolactone that enhances chromatin accessibility and primes fibroblasts for improved sensitivity to low-dose chemical stimuli in a short period. The scaffold mimics the extracellular matrix, providing topographical cues that reduce cytoskeletal tension and promote nuclear deformation, thereby increasing chromatin openness.
View Article and Find Full Text PDFBMC Public Health
September 2025
Department of Medicine, Huddinge, Karolinska Institutet, 141 83, Huddinge, Sweden.
Background: Preschools are important environments in shaping young children's lifestyle behaviours, including movement (physical activity, screen time, and sleep) and eating behaviours. Few studies have investigated how teachers and principals can be supported in promoting healthy lifestyle behaviours in the preschool setting and whether a digital support tool could be a way forward. This study aimed to explore preschool teachers' and principals' perceptions, needs, and prerequisites for promoting healthy lifestyle behaviours, as well as their preferences for a potential digital support.
View Article and Find Full Text PDFPediatr Res
September 2025
Division of Developmental and Behavioral Pediatrics, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Background: Children with congenital cytomegalovirus (cCMV) have a wide spectrum of possible neurodevelopmental outcomes.
Objectives: To describe neurodevelopmental (ND) Phenotypes of children with cCMV based on medical, developmental, and behavioral outcomes in childhood, and examine whether birth characteristics were associated with ND Phenotype.
Methods: Caregivers of children with cCMV (N = 242, child aged 12 months to <11 years) completed survey instruments reporting on the child's birth characteristics, reasons for cCMV testing, and present medical, developmental, and behavioral status.
JMIR Res Protoc
September 2025
School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Background: Electronic health records (EHRs) have been linked to information overload, which can lead to cognitive fatigue, a precursor to burnout. This can cause health care providers to miss critical information and make clinical errors, leading to delays in care delivery. This challenge is particularly pronounced in medical intensive care units (ICUs), where patients are critically ill and their EHRs contain extensive and complex data.
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