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Background: Induction of labor (IOL) is an increasingly common intervention, but experiences and preferences of induction methods are under-researched particularly in low -and middle-income countries. Understanding these perspectives is important to improve the childbirth experience.
Objective: To explore the experiences and preferences of IOL methods for women, clinicians, and researchers in the "Misoprostol or Oxytocin for Labour Induction" (MOLI) study.
Study Design: This qualitative study was based in two government hospitals in the city of Nagpur, India-one tertiary referral hospital and one women's hospital. Fifty-three semi-structured interviews with women before and after induction (between days 1 and 5 postnatal), with women recruited to the "Misoprostol or Oxytocin for Labour Induction (MOLI)" randomized controlled trial (NCT03749902). Eight focus group discussions with doctors, nurses, and trial research assistants before and during trial delivery were conducted. Thematic analysis was conducted using the Framework approach.
Results: Four themes emerged: (1) (2) (3) , and (4) For women, the safety of their baby was more important than any IOL method. Clinicians had apprehensions over misoprostol use which could affect protocol implementation; they reported that changing perception is difficult as usual practice feels "comfortable." Women wanted to share their experiences and reported key moments during childbirth including vaginal examinations, "trying for normal," bearing the pain, waiting, and relationships with staff.
Conclusion: Women did not have a strong preference for the IOL method and viewed childbirth positively when maternal and neonatal outcomes were good. Labor pain, vaginal examinations, a normal birth, and interactions with staff impacted women's experiences.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415567 | PMC |
http://dx.doi.org/10.1016/j.xagr.2024.100389 | DOI Listing |
Med Acupunct
August 2025
Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.
Introduction: Acupuncture has emerged as an effective adjunctive therapy for polycystic ovary syndrome (PCOS) with concern on the higher rate of adverse events (AE). In addition, timing of intervention, specific acupoints, and stimulation strength are concerning, as high-stimulation electroacupuncture (EA) may increase miscarriage risk. This review aims to systematically evaluate the safety profile of acupuncture in PCOS.
View Article and Find Full Text PDFFront Vet Sci
August 2025
Faculty of Fisheries, Recep Tayyip Erdogan University, Rize, Türkiye.
Application of anesthetic chemicals in aquaculture is important to minimize stress under normal operations such as handling, transport, and artificial breeding. In the past decade, the preference for natural anesthetics over synthetic ones has increased due to welfare issues regarding fish welfare and food safety. This study investigates the anesthetic efficacy of nutmeg oil () in three freshwater fish species- (Common carp), (Danube sturgeon), and (Rainbow trout)-by modeling behavioral (Induction and recovery times) and hematological responses using artificial neural networks (ANNs).
View Article and Find Full Text PDFIntroduction: Breast cancer incidence has been rising in recent years, particularly among younger women, and it is now the leading cancer among Indian females. Acute postoperative pain is a significant concern, often deterring patients from surgery. Combining regional anesthesia with intravenous analgesics can improve postoperative outcomes.
View Article and Find Full Text PDFCureus
August 2025
Anaesthesiology, Latifa Hospital, Dubai Health, Dubai, ARE.
Propofol and thiopental are commonly used induction agents for general anesthesia in cesarean sections. While both are effective, their impact on neonatal outcomes, particularly Apgar scores, remains a subject of clinical interest. Neonatal Apgar scores are critical indicators of early adaptation and are used to assess the immediate well-being of the newborn after delivery.
View Article and Find Full Text PDFCureus
August 2025
Department of Anesthesiology and Critical Care, GSVM (Ganesh Shankar Vidyarthi Memorial) Medical College, Kanpur, IND.
Introduction: The goal of perioperative management in reactive airway disease (RAD) patients is to ensure optimal airway stability, maintain adequate oxygenation, and reduce the need for mechanical ventilation while minimizing airway irritation and inflammation. Due to the airway hyperresponsiveness and increased risk of respiratory complications in RAD patients, non-opioid adjuncts that provide both bronchodilation and analgesia are preferred. Lignocaine and magnesium sulfate (MgSO₄) have emerged as effective agents in this context.
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