98%
921
2 minutes
20
This case report describes the discovery of a type 1 retroaortic left renal vein (RLRV) in an 83-year-old male cadaveric donor with multiple comorbidities. RLRV is an anatomical variant with an estimated incidence of 0.5-3.6%, with type 1 RLRV being the most common subtype. RLRV is typically asymptomatic, which aligns with the benign nature of the anatomical variation seen in this case. However, it is important to recognize that RLRV can be symptomatic. The hallmark manifestations of renal vein entrapment, colloquially known as the "nutcracker syndrome," include hematuria, proteinuria, flank pain, and varicocele, which are concurrent with the encasement of the renal vein between the aorta and surrounding anatomical structures. RLRV is typically diagnosed using multidetector CT (MDCT) or Doppler ultrasound (DUS). The therapeutic approach to symptomatic RLRV primarily encompasses conservative strategies, such as the administration of angiotensin-converting enzyme (ACE) inhibitors and aspirin, whereas surgical interventions are generally reserved for refractory cases, i.e., when conservative measures fail to alleviate the symptoms.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11412091 | PMC |
http://dx.doi.org/10.7759/cureus.67296 | DOI Listing |
Mol Pharm
September 2025
Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an 710061, PR China.
Acute kidney injury (AKI) is a common clinical syndrome characterized by abnormal renal function and structure. Microcirculatory perfusion disorders and inflammatory responses are critical pathophysiologies of AKI. Recently, ultrasound molecular imaging has been considered a valuable tool for preclinical and clinical diagnostics that can sensitively target histological structures of interest, particularly in evaluating renal microcirculation.
View Article and Find Full Text PDFAnn Afr Med
September 2025
Department of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Background: A comprehensive knowledge of renal vasculature is essential to diagnose and carry out safe clinical interventions accurately. Anatomic variations in renal vessels can present procedural challenges in surgeries such as nephrectomy, transplants, and endovascular interventions.
Methods: In the present retrospective study, we analyzed the distribution patterns of the renal vascular variants and measurements of length and diameter in computed tomography angiographies (CTAs).
World J Urol
September 2025
Department of Urology and Transplantation Surgery, Nantes University Hospital, Nantes, France.
Purpose: In 5-10% of cases, renal cancer extends into the venous system, particularly the inferior vena cava (IVC), which worsens prognosis. This study aims to assess morbidity, mortality, and oncological outcomes of patients treated surgically for renal cancer with IVC extension over a 30-year period, in two experienced centers.
Materials And Methods: This bicentric, retrospective study analyzed patients treated between 1988 and 2020 for renal cancer involving the IVC.
Arch Esp Urol
August 2025
Department of Nephrology, The Fourth Hospital of Changzhou, 231002 Changzhou, Jiangsu, China.
Objective: To explore the impact of Tripterygium wilfordii glycosides (TWG) on glomerulosclerosis within a rat model of chronic kidney disease (CKD), as well as the role of the transforming growth factor-β1 (TGF-β1)/Smad signaling pathway in this mechanism.
Methods: Twenty-four clean Sprague-Dawley rats were divided into Sham group (n = 8), model group (n = 8) and TWG group (n = 8). Adriamycin nephropathy (ADRN) rat model was established by jugular vein injection of adriamycin (ADR).
Medicine (Baltimore)
September 2025
Department of Nephrology and Blood Purification, Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
Rationale: This case report aims to highlight a rare but life-threatening complication of femoral venous catheterization and to describe a novel endovascular technique for its management. Non-tunneled femoral catheters provide rapid vascular access for emergency dialysis (e.g.
View Article and Find Full Text PDF