The Fundoplication Revision of a Recurrent Large Paraesophageal Hiatal Hernia in a 63-Year-Old Female.

Paraesophageal hiatal hernias present significant clinical challenges due to their potential for incarceration and strangulation. The high risk of recurrence can also pose difficulties in management. We report a case of a 63-year-old Caucasian female with a history of recurrent paraesophageal hiatal hernia, initially diagnosed after a gastric incarceration event in 2014.

Identifying Aspirin as a Contributing Factor to Persistent Gout: A Case Report.

Gout is a metabolic disorder characterized by acute and chronic inflammatory responses due to monosodium urate (MSU) crystal deposition, commonly affecting the first metatarsophalangeal joint, hands, and/or knees. While this condition is typically self-limiting, recurrent cases can suggest an underlying contributor. Low-dose aspirin is commonly used as a cardiovascular prophylaxis.

An Uncommon Anatomical Variation: Passage of the Ovarian Artery Through a Fenestrated Ovarian Vein in an Elderly Female Cadaver.

Ovarian vein fenestration is an extremely rare vascular anomaly characterized by the temporary splitting and rejoining of the ovarian vein. Unlike duplication, fenestration involves a single vein dividing into multiple channels before converging again; it is often discovered incidentally during imaging or surgical procedures. This case report highlights a rare anatomical variant involving the ovarian artery and vein observed in an elderly female cadaver.

A Rare Case of Right Renal Vein Entrapment: A Cadaveric Study.

Renal vein entrapment, especially concerning the right renal vein, represents a scarcely explored anatomical aberration. The right renal vein's pivotal role in renovascular renal hemodynamics underlines the clinical significance of its compression, which can precipitate an elevated renal venous pressure gradient in relation to the inferior vena cava. This report delineates a unique instance of right renal vein entrapment in a 92-year-old male cadaver, identified during routine dissection.

Paget-Schroetter Syndrome: A Case of a Young Weightlifter.

Venous thoracic outlet syndrome is a rare type of thoracic outlet disorder that is often overlooked. When an upper extremity deep vein thrombosis (UEDVT) occurs due to thoracic outlet compression, it is commonly referred to as Paget-Schroetter syndrome (PSS). The space between the first rib and the clavicle where the subclavian vein passes through is highly vulnerable to compression and injury.

Pharmaceuticals and personal care products: A critical review of the impacts on fish reproduction.

Research in environmental toxicology involving pharmaceuticals and personal care products (PPCPs) has increased greatly over the last 10-15 years. Much research has been focused on the endocrine-disrupting potential of PPCPs, as they relate to negative population impacts of aquatic organisms. This review assesses the current data on the reported effects of PPCPs on fish reproduction with an emphasis on fecundity, a predictor of population effects.

Responses to various exposure durations of levonorgestrel during early-life stages of fathead minnows (Pimephales promelas).

Pharmaceuticals are routinely detected in the environment; and several of these compounds have been extensively researched due to their potential impacts to the endocrine system of aquatic organisms. The negative reproductive consequences of synthetic progestins in teleost species have only recently been investigated. The current study examined different exposure periods that may be most sensitive for levonorgestrel (LNG) in early-life stages of fathead minnow larvae.

Levonorgestrel exposure to fathead minnows (Pimephales promelas) alters survival, growth, steroidogenic gene expression and hormone production.

Human pharmaceuticals are commonly detected in the environment. Concern over these compounds in the environment center around the potential for pharmaceuticals to interfere with the endocrine system of aquatic organisms. The main focus of endocrine disruption research has centered on how estrogenic and androgenic compounds interact with the endocrine system to elicit reproductive effects.

Involvement of β(3)-adrenergic receptors in in vivo cardiovascular regulation in rainbow trout (Oncorhynchus mykiss).

Currently, we have little information concerning the involvement of β(3)-adrenergic receptors (AR) in cardiovascular regulation in fishes. The goal of this study was to investigate the effect of β(3)-AR ligands on in vivo cardiovascular function in larval and adult rainbow trout (Oncorhynchus mykiss). In adult fish, injection of BRL(37344) (β(3)-AR agonist) resulted in an increase in heart rate (f(H)) (~31%) while stroke volume (Sv) was reduced (-25.