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Purpose: To document how acute cerebrovascular accidents (CVAs) present first to an ophthalmologist.
Methods: Retrospective, observational, unicentric hospital-based study. The electronic medical records of new patients who presented to the Neuro-ophthalmology department of a tertiary eye hospital in the month of August 2022 were reviewed. Those with symptoms suggestive of an acute stroke requiring urgent neuroimaging were chosen for further study.
Results: Out of the 710 new patients, 31 had a known CVA and presented with field defects (4.3%). We recognized nine new patients, subsequently diagnosed to have a CVA, initially presenting with ocular symptoms such as homonymous hemianopia in seven cases and two others as transient obscuration of vision and internuclear ophthalmoplegia.
Conclusion: Posterior circulation strokes commonly present first to an ophthalmologist, the early recognition of which is of utmost importance.
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http://dx.doi.org/10.4103/IJO.IJO_2456_23 | DOI Listing |
Am J Ophthalmol
September 2025
Department of Ophthalmology, York Hospital, York, UK.
Historical medical texts can reveal overlooked therapeutic approaches relevant to modern ophthalmology. This perspective revisits a remedy from the Babylonian Talmud prescribing a mixture of scorpion and kohl for an eye condition called buruqti (also transliterated as beroketi), traditionally translated as cataract. Through philological, zoological, and pathological analysis, we argue that buruqti likely refers to a corneal or conjunctival lesion rather than a true lens opacity.
View Article and Find Full Text PDFACS Nano
September 2025
MOE International Joint Research Laboratory on Synthetic Biology and Medicines, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Significant advances in science and engineering often emerge at the intersections of disciplines. Nanoscience and nanotechnology are inherently interdisciplinary, uniting researchers from chemistry, physics, biology, medicine, materials science, and engineering. This convergence has fostered novel ways of thinking and enabled the development of materials, tools, and technologies that have transformed both basic and applied research, as well as how we address critical societal challenges.
View Article and Find Full Text PDFAdv Ophthalmol Pract Res
July 2025
Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Background: Retinal vein occlusion (RVO) is a leading cause of visual impairment on a global scale. Its pathological mechanisms involve a complex interplay of vascular obstruction, ischemia, and secondary inflammatory responses. Recent interdisciplinary advances, underpinned by the integration of multimodal data, have established a new paradigm for unraveling the pathophysiological mechanisms of RVO, enabling early diagnosis and personalized treatment strategies.
View Article and Find Full Text PDFApoptosis
August 2025
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Age-related macular degeneration (AMD) is currently the leading cause of vision loss in developed countries. Despite decades of research and development, there are currently no treatments for the dry version of the illness. Dry AMD (DAMD) is a multifactorial disease stemming from dysfunction in the complement system, mitochondrial function, and lipid metabolism.
View Article and Find Full Text PDFTransl Vis Sci Technol
August 2025
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, People's Republic of China.
Purpose: Accurate assessment and surveillance of retinoblastoma (RB) require more efficient and objective measurements. This study aims to develop an artificial intelligence (AI) system, named RB-Care, for automatic classification and quantitative assessment of RB.
Methods: A total of 3730 wide-field fundus images were included for the development and validation of 2 models in RB-Care.