Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: To evaluate the usefulness of novel diffusion-weighted imaging (DWI) findings for diagnosing placenta accreta spectrum (PAS).
Materials And Methods: This retrospective study included 49 pregnant women with suspected PAS who underwent 1.5 T placental MRI. Diffusion lacunae were defined as intraplacental areas showing hypointensity on DWI and hyperintensity on the apparent diffusion coefficient map. Two radiologists evaluated the number and size of placental lacunae on DWI, and flow void in the diffusion lacunae on T2-weighted imaging. The radiologists also evaluated established MRI features of PAS described in the SAR-ESUR consensus statement. Pearson's chi-square test or Mann-Whitney U test was used to compare findings between patients with and without PAS. Interobserver reliability for DWI and established MRI features was also assessed. Optimal thresholds for the number and maximum size of diffusion lacunae for differentiating PAS from the no-PAS group were determined using receiver operating characteristic curve analyses.
Results: Eighteen patients were diagnosed with PAS, and 31 patients with placental previa without PAS. The number and maximum size of diffusion lacunae were significantly larger in patients with than in patients without PAS (p < 0.0001). Combining assessment of the number of diffusion lacunae with assessment of their maximum size yielded a diagnostic performance with sensitivity, specificity and accuracy of 83%, 94% and 90%, respectively. Flow voids within the diffusion lacunae had sensitivity, specificity and accuracy of 88%, 84% and 86%, respectively.
Conclusion: The number and size of diffusion lacunae, and T2 flow void in diffusion lacunae may be useful findings for diagnosing PAS.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11790739 | PMC |
| http://dx.doi.org/10.1007/s11604-024-01657-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Gradients in lacunar morphology and cartilage mineralization reflect the mechanical function of the mouse femoral head epiphysis.
Acta Biomater
July 2025
Department of Engineering, Faculty of Environment, Science and Economy, University of Exeter, Exeter, UK. Electronic address:
Mouse femurs are widely used to study bone development and disorders. The mammalian femoral head epiphysis, located between articular cartilage and a growth plate, critically maintains joint integrity during weight-bearing and supports femoral growth. Murine femoral head epiphyses are unusual in having no secondary ossification center (SOC).
View Article and Find Full Text PDFSurrogate modeling of Cellular-Potts Agent-Based Models as a segmentation task using the U-Net neural network architecture.
ArXiv
May 2025
Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.
The Cellular-Potts model is a powerful and ubiquitous framework for developing computational models for simulating complex multicellular biological systems. Cellular-Potts models (CPMs) are often computationally expensive due to the explicit modeling of interactions among large numbers of individual model agents and diffusive fields described by partial differential equations (PDEs). In this work, we develop a convolutional neural network (CNN) surrogate model using a U-Net architecture that accounts for periodic boundary conditions.
View Article and Find Full Text PDFPurpose: The clinical use and efficacy of phytomolecules are often hampered as their complex structure, poor aqueous solubility and low biological stability restricts their intestinal permeability which results in low oral bioavailability. Rutin (RT), quercetin (QU), thymoquinone (TQ) are few of such potent and therapeutically versatile phytomolecules that await maximal utilization. To address this lacuna, an attempt was made to develop a single strategy for enhanced intestinal permeation that can be applied to diverse phytomolecules.
View Article and Find Full Text PDFEffects on Mass Transfer in the Bone Lacunar-Canalicular System under Different Radial Extracorporeal Shock Waves.
Tissue Eng Regen Med
April 2025
Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, School of Mechanical Engineering, Tianjin University of Technology, Tianjin, 300384, China.
Background: The bone lacunar-canalicular system (LCS) is an important microscopic infrastructure for signaling and solute transport in bone tissue, which guarantees the normal physiological processes of bone tissue, and there is a direct relationship between osteoporosis and intrabody mass transfer; however, the mass transfer pattern of the LCS has not yet been clarified under different intensities of in extracorporeal shock waves. The present study aims to assess the effect of extracorporeal shock waves on mass transfer in LCS.
Methods: Sodium fluorescein tracer was taken as the transport substance, and the fluorescence intensities of osteocytes at lacuna in bovine cortical bone were used to indicate the mass transfer effect.
Association of glymphatic clearance function with imaging markers and risk factors of cerebral small vessel disease.
J Stroke Cerebrovasc Dis
February 2025
Department of Radiology, Zigong First People's Hospital, Zigong, PR China. Electronic address:
Background: Cerebral small vessel disease (CSVD) is a common disease in the elderly, and its pathogenesis is still being explored. Glymphatic clearance function can be evaluated by diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index. This study aims to investigate the changes in glymphatic clearance function in CSVD patients and its relationship with imaging markers and risk factors of CSVD.
View Article and Find Full Text PDF