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A 78-year-old man with a previous diagnosis of rheumatoid arthritis on prolonged treatment with corticosteroids presented with intense and progressive pain at the cervical level that prevented him from resting his head and walking, in addition to an ulcerative lesion covering 80% of the lingual area that was previously treated as oral candidiasis without improvement. On arrival, with no clinical or serological data of rheumatoid arthritis, immunosuppressive treatment was suspended, and a biopsy of the oral cavity was requested, confirming the diagnosis of lingual tuberculosis, an extremely rare disease, occurring in less than 1% of extrapulmonary cases. MRI of the cervical spine showed a crush fracture of the C6 and C7 bodies associated with spondylitis of probably infectious etiology that required surgical treatment, and histopathological studies confirmed Pott's disease. The patient displayed no evidence of pulmonary tuberculosis from arrival until the end of the follow-up.
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http://dx.doi.org/10.3390/medicina60081282 | DOI Listing |
Front Neurol
August 2025
Department of Infectious Diseases, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Aims: In this study, we aimed to analyze the pathogen detection results in spinal infections using percutaneous CT-guided biopsy or transforaminal endoscopic spinal biopsy.
Methods: This is a retrospective observational study of patients who underwent biopsy for spinal infection at Shanghai Sixth People's Hospital between December 2020 and June 2024. Data on demographics, clinical presentations, radiological findings, and histopathology were collected from medical records.
Medicine (Baltimore)
August 2025
Department of Ultrasound, Kunming Medical University Affiliated Qujing Hospital, Qujing, China.
Rationale: Lawsonella clevelandensis is a gram-positive bacterium, partially acid-fast, strictly anaerobic, nonspore-forming, and catalase-positive. This microorganism was once overlooked in clinical microbiology due to its stringent growth requirements in laboratory cultures, but it has recently attracted recognition as a potential pathogen. Available reports implicate Lawsonella clevelandensis infection with abscess formation, including breast, spinal, abdominal, and deep soft tissue abscesses.
View Article and Find Full Text PDFBMC Musculoskelet Disord
September 2025
Departments of Orthopedics, Hangzhou Ninth People's Hospital, Hangzhou, Zhejiang, 310000, China.
Background: The burden of spinal tuberculosis (STB) in China remains substantial, with the country ranking third in the number of tuberculosis cases globally in 2022, among the 30 countries with a high tuberculosis burden. In East China, few large-scale studies have been conducted on STB.
Methods: This retrospective study analyzed 893 confirmed STB cases (2010-2020).
J Neurosurg Case Lessons
September 2025
Department of Pathology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Occlusion of the foramen of Monro is an exceedingly rare condition in adults and can lead to obstructive hydrocephalus. The authors present the first reported case of biventricular hydrocephalus caused by tuberculosis-induced bilateral obstruction of the foramen of Monro. They also discuss the technical nuances and surgical challenges associated with this condition.
View Article and Find Full Text PDFPurpose: Spinal tuberculosis (STB) remains prevalent in developing nations and significantly contributes to morbidity, often resulting in kyphotic deformity and neurological deficits. In this study, we correlate the diagnostic, therapeutic and prognostic factors according to the current standard of management of STB.
Methods: This retrospective study evaluated diagnostic and prognostic factors in 77 patients with STB treated surgically (37.