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Medicinal plants play a pivotal role in traditional medicine and modern pharmacology due to their various bioactive compounds. However, heat stress caused by climate change will seriously affect the survival and quality of medicinal plants. In this review, we update our understanding of the research progress on medicinal plants' response mechanisms and control measures under heat stress over the last decade. This includes physiological changes, molecular mechanisms, and technical means to improve the heat tolerance of medicinal plants under heat stress. It provides a reference for cultivating heat-resistant varieties of medicinal plants and the rational utilization of control measures to improve the heat resistance of medicinal plants.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11355039 | PMC |
http://dx.doi.org/10.3390/ijms25168600 | DOI Listing |
Cell Mol Biol (Noisy-le-grand)
September 2025
IQRAA Centre for Research and Development, IQRAA International Hospital and Research Centre, Kozhikode, Kerala, India.
Terminalia arjuna, an important medicinal plant in traditional Indian systems, has been extensively studied for its cardioprotective bark. However, limited attention has been given to its fruit, which contains several biologically active phytochemicals with potential antioxidant, anti-inflammatory, and immunomodulatory properties. This study aimed to isolate and partially purify phytoactive compounds from the fruit of T.
View Article and Find Full Text PDFArch Microbiol
September 2025
School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Endophytic fungi are nonpathogenic fungi that live symbiotically in the interior of healthy plant tissues and form mutualistic associations with their hosts. These fungi are critically involved in promoting plant development, strengthening plant uptake of nutrients, and improving plant resistance to biotic and abiotic stress conditions. Endophytic fungi improve plant growth by synthesizing phytohormones (e.
View Article and Find Full Text PDFInt J Nanomedicine
September 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, People's Republic of China.
Exosomes are nano-sized extracellular vesicles secreted by diverse cell types that mediate intercellular communication through the transfer of proteins, lipids, and nucleic acids. Their ability to cross biological barriers and carry bioactive cargo has led to increasing interest in their use as targeted delivery systems for drugs, genes, and immunomodulatory molecules. Recently, plant-derived exosome-like nanoparticles, PLNs obtained from edible plants and medicinal herbs have emerged as a novel, biocompatible alternative to mammalian exosomes.
View Article and Find Full Text PDFFood Sci Biotechnol
October 2025
Department of Biomedical Technology, Kangwon National University, Chuncheon, Republic of Korea.
This study investigated the anti-periodontitis effects of MENP (mixed extracts from multiple natural plants with a certain percentage). Lipopolysaccharide from (LPS-PG) was used to stimulate Raw 264.7 and human gingival fibroblast-1 cells.
View Article and Find Full Text PDFACS Omega
September 2025
Neuroscience and Ageing Biology Division, CSIR- Central Drug Research Institute (CDRI), Lucknow 226031, India.
The TRPA1 channel has recently emerged as a critical target for pain relief since its antagonists target the beginning of the pain transduction pathway and, thus, are devoid of side effects such as sedation, dizziness, somnolence, or cognitive impairment. Despite this clinical significance, currently, no TRPA1 inhibitors suitable for therapeutic usage exist to target these channels. Since ancient times, natural products have been known to be a rich source of new drugs, useful therapeutic agents, as well as pharmacological tools.
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