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Blinking contributes to the health and protection of the eye and also holds potential in the context of muscle or nerve disorder diagnosis. Traditional methods of classifying eye blinking as open or closed are insufficient, as they do not capture medical-relevant aspects like closure speed, duration, or percentage. The issue could be solved by reliably detecting blinking intervals in high-temporal recordings. Our research demonstrates the reliable detection of blinking events through data-driven analysis of the eye aspect ratio. In an unsupervised manner, we establish an eye state prototype to identify blink intervals and measure inter-eye synchronicity between moments of peak closure. Additionally, our research shows that manually defined prototypes yield comparable results. Our results demonstrate inter-eye synchronicity up to 4.16 ms. We anticipate that medical professionals could utilize our methods to identify or define disease-specific prototypes as potential diagnostic tools.
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http://dx.doi.org/10.3233/SHTI240731 | DOI Listing |
Retin Cases Brief Rep
September 2025
Retinal Disorders and Ophthalmic Genetics Division, Stein Eye Institute, University of California of Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Purpose: To describe a case of recalcitrant bilateral peripapillary pachychoroid syndrome (PPS) treated with high-dose (HD) intravitreal aflibercept injections.
Methods: Medical and imaging records were retrospectively evaluated. Multimodal imaging included ultra-widefield indocyanine green and fluorescein angiography and fundus autofluorescence.
iScience
September 2025
College of Electronic Science and Technology, National University of Defense Technology, Changsha 410073, China.
Monopulse radar angle measurement technology is crucial for modern missile precision guidance systems due to its high accuracy and real-time capabilities. Cross-eye jamming (CEJ) is recognized as one of the most effective countermeasures against monopulse radar. However, traditional CEJ implementation requires complex amplitude and phase modulation through specialized hardware.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Ophthalmology and Visual Sciences, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, United States.
Ocular trauma disproportionately impacts low- and middle-income countries (LMICs) and contributes significantly to blindness and disability in these settings. While numerous publications address the epidemiology of ocular trauma in limited-resource settings, there are no systematic reviews, meta-analyses, or large-scale review articles investigating this topic further. In this article, the authors summarize, compare, and contrast the extant literature on ocular trauma in LMICs.
View Article and Find Full Text PDFFront Cell Neurosci
August 2025
Stem Cell Research Center, University of California, Irvine, Irvine, CA, United States.
Objective: To assess the safety and tolerability of intravitreal injection of human retinal progenitor cells (RPCs) at multiple dose levels in adults with non-syndromic retinitis pigmentosa (RP).
Design: A prospective, multicenter, open-label, single-arm, Phase I/IIa safety study of RPCs in adults with RP ( = 28). Two patient cohorts were studied: Cohort 1: BCVA no better than 20/200 and no worse than Hand Motions, and Cohort 2: BCVA no better than 20/40 and no worse than 20/200).
Cureus
August 2025
Ophthalmology, Cornea and Refractive Surgery, John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, USA.
Purpose This study aims to compare the initial three-month outcomes of a single-center experience with small incision lenticule extraction (SMILE) for correction of myopia and myopic astigmatism using the VisuMax 500 (Carl Zeiss Meditec, Jena, Germany) versus the VisuMax 800 (SMILE Pro®; Carl Zeiss Meditec, Jena, Germany). This experience is compared to the US Food and Drug Administration approval studies and published literature. Patients and methods The initial 45 eyes (23 patients) that underwent SMILE with the VisuMax 500 in 2018 were compared with the initial 42 eyes (21 patients) that underwent SMILE Pro® with the VisuMax 800 in 2024.
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