Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Screen-printed carbon electrodes (SPCE) functionalized with MXene-based three-dimensional nanomaterials are reported for rapid determination of creatinine. TiCT MXene with in situ reduced AuNPs (MXene@AuNP) were used as a coreactant accelerator for efficient immobilization of enzymes. Creatinine could be oxidized by chitosan-embedded creatinine amidohydrolase, creatine amidinohydrolase, or sarcosine oxidase to generate HO, which could be electrochemically detected enhanced by Prussian blue (PB). The enzyme@CS/PB/MXene@AuNP/SPCE detected creatinine within the range 0.03-4.0 mM, with a limit of detection of 0.01 mM, with an average recovery of 96.8-103.7%. This indicates that the proposed biosensor is capable of detecting creatinine in a short amount of time (4 min) within a ± 5% percentage error, in contrast with the standard clinical colorimetric method. With this approach, reproducible and stable electrochemical responses could be achieved for determination of creatinine in serum, urine, or saliva. These results demonstrated its potential for deployment in resource-limited settings for early diagnosis and tracking the progression of chronic kidney disease (CKD).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00604-024-06606-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of dietary faba bean ( L.) inclusion on carcass characteristics, meat quality, and blood biochemistry in Awassi lambs.
Vet World
July 2025
Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Pulau Pinang, Malaysia.
Background And Aim: The search for sustainable and cost-effective protein alternatives to soybean meal in livestock diets has led to the exploration of legumes such as faba beans [FBs] ( L.). This study investigated the effects of dietary inclusion of FBs on carcass traits, meat quality, and selected blood parameters in Awassi lambs.
View Article and Find Full Text PDFArsenic-induced nephrotoxicity: Mechanisms, biomarkers, and preventive strategies for global health.
Vet World
July 2025
Department of Basic Medical Sciences, Division of Physiology, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Arsenic exposure remains a critical global health concern, with growing evidence linking it to significant kidney dysfunction. This review examines the underlying mechanisms of arsenic-induced nephrotoxicity, including oxidative stress, mitochondrial dysfunction, inflammation, and programmed cell death, which collectively contribute to damage in the glomeruli and renal tubules. Chronic exposure is associated with proteinuria, renal impairment, and an increased risk of chronic kidney disease (CKD).
View Article and Find Full Text PDFA Rare Case of Plasmablastic Myeloma After Renal Transplant.
Exp Clin Transplant
August 2025
>From the University Clinic for Nephrology, Faculty of Medicine, Saints Cyril and Methodius University in Skopje, Skopje, North Macedonia.
Posttransplant lymphoproliferative disorders are a serious complication after solid-organ transplant, with a reported incidence from 2% to 20%. Plasma cell neoplasms in solid-organ transplants represent a rare but increasingly serious complication after solid-organ transplant. We report a case of plasmablastic myeloma, a very rare variant of multiple myeloma with aggressive course and poor prognosis.
View Article and Find Full Text PDFLate Effect of Early Phase COVID-19 on Outcomes of Kidney Transplant Recipients Who Survived the Acute Infection.
Exp Clin Transplant
August 2025
>From the Division of Nephrology and Kidney Transplantation, Hospital de Clínicas de Porto Alegre, Brazil.
Objectives: The COVID-19 pandemic has significantly affected global health, particularly among high-risk populations such as kidney transplant recipients, who have exhibited elevated morbidity and mortality rates. Long-term effects of COVID-19 in kidney transplant recipients who survived the infection are unknown. We evaluated the long-term effects of early phase COVID-19 on patient and graft survival, as well as graft function, in kidney transplant recipients who survived the acute phase of the COVID-19 infection.
View Article and Find Full Text PDFConstruction of a nomogram for hypertriglyceridemic severe acute pancreatitis that includes metabolic indexes.
Lipids Health Dis
September 2025
Department of Gastroenterology, Weifang People's Hospital, The First Affiliated Hospital of Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China.
Background: Current scoring systems for hypertriglyceridaemia-induced acute pancreatitis (HTG-AP) severity are few and lack reliability. The present work focused on screening predicting factors for HTG-SAP, then constructing and validating the visualization model of HTG-AP severity by combining relevant metabolic indexes.
Methods: Between January 2020 and December 2024, retrospective clinical information for HTG-AP inpatients from Weifang People's Hospital was examined.