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We examine the influence of density on the transition between chain and spiral structures in planar assemblies of active semiflexible filaments, utilizing detailed numerical simulations. We focus on how increased density, and higher Péclet numbers, affect the activity-induced transition spiral state in a semiflexible, self-avoiding active chain. Our findings show that increasing the density causes the spiral state to break up, reverting to a motile chain-like shape. This results in a density-dependent reentrant phase transition from spirals back to open chains. We attribute this phenomenon to an inertial effect observed at the single polymer level, where increased persistence length due to inertia has been shown in recent three-dimensional studies to cause polymers to open up. Our two-dimensional simulations further reveal that a reduction in the damping coefficient leads to partial unwinding of the spirals, forming longer arms. In suspension, interactions among these extended arms can trigger a complete unwinding of the spirals, driven by the combined effects of density and inertia.
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http://dx.doi.org/10.1039/d4sm00572d | DOI Listing |
Calcif Tissue Int
September 2025
Department of Physical Education, Center for Health and Sports Sciences, Santa Catarina State University, Rua Pascoal Simone, 358, Coqueiros, Florianópolis, State of Santa Catarina, CEP: 88080-350, Brazil.
This study investigated the association between energy and macronutrient intake and bone health in 63 adolescents of both sexes who participated in volleyball, track and field, or swimming. Bone mineral content (BMC) and density (BMD) of the total body less head (TBLH), lumbar spine (L1-L4), and femoral neck were assessed using DXA. Bone geometry parameters, including cross-sectional area (CSA), cross-sectional moment of inertia (CSMI), and section modulus, were estimated.
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November 2025
Centre for Orthopaedic and Trauma Research, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia; Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Adelaide, SA, Australia.
Carboxylated osteocalcin (cOC), produced during post-translational modification of osteocalcin (OC) in a vitamin K-dependent pathway, has a high affinity for calcium and hydroxyapatite. Despite the observed link between vitamin K deficiency and fracture risk, supplementation studies have not consistently demonstrated improvements in bone mineral density (BMD) or bone microarchitecture, though studies have reported improvement in cOC status. We hypothesise that these inconsistent findings are due to the lack of knowledge on the mechanisms by which cOC affects bone health.
View Article and Find Full Text PDFBMC Cardiovasc Disord
August 2025
Division of Cardiology, Cardio-Cerebrovascular Center, Konyang University Hospital, 158, Gwanjeodong-Ro, Seo-Gu, Daejeon, 35365, Republic of Korea.
Background: Therapeutic inertia is defined as the failure to provide guideline-directed therapy and is a barrier to achieving optimal clinical outcomes. We aimed to evaluate therapeutic inertia in statin therapy after percutaneous coronary intervention (PCI) and its association with patient characteristics and physician’s prescribing practice.
Methods: We analyzed the medical claims data on patients undergoing PCI using National Health Insurance Service in Republic of Korea.
Entropy (Basel)
July 2025
College of Power Engineering, Naval University of Engineering, Wuhan 430033, China.
Gas turbines in land-based microgrids and shipboard-isolated power grids frequently face operational challenges, such as the startup and shutdown of high-power equipment and sudden load fluctuations, which significantly impact their performance. To examine the dynamic behavior of gas turbines under transitional operating conditions, a three-dimensional computational fluid dynamic simulation is employed to create a model of the gas turbine rotor, incorporating thermal inertia, which is then analyzed in conjunction with three-dimensional finite element methods. The governing equations of the flow field are discretized, providing results for the flow and temperature fields throughout the entire flow path.
View Article and Find Full Text PDFBehav Res Ther
July 2025
Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA. Electronic address:
Adolescence is a critical developmental period marked by an elevated risk for Major Depressive Disorder (MDD). Identifying predictive risk factors is crucial for the development and timely delivery of preventative interventions. One potential risk factor is maladaptive and rigid emotion dynamics, which findings suggest is linked with depressive symptoms.
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