Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Aim: To review our 10 years of experience with the endoscopic treatment of vesicoureteral reflux (VUR) in children, emphasizing the long-term efficacy of the "combined STING-HIT" technique.
Materials And Methods: A retrospective study was performed including all children with symptomatic VUR undergoing the cystoscopic injection of bulking agents from January 2013 to December 2022 in our pediatric tertiary referral center. Three different endoscopic techniques were adopted: the "combined STING-HIT" technique, the STING technique, and the HIT technique. Treatment success was defined as symptom remission and VUR resolution on the voiding cystourethrogram (VCUG) performed at the 3-month follow-up.
Results: In the study period, 140 (F:M = 64:76) patients and 228 ureters were treated at a median patient age of 3 (2.0-6.0) years. After a single endoscopic treatment, VUR resolved in 203 (88%) ureters. The VUR resolution rate after a single endoscopic treatment was 95% (n=70/74) in case of I-II VUR, 88% (n=87/99) in case of III VUR; 83% (n=38/46) in case of IV VUR; 89% (n=8/9) in case of V VUR (p-value: 0.174). Overall, one or two endoscopic treatments succeeded in 219 (96%) ureters. The overall VUR resolution rate following one or two endoscopic treatments was 100% (74/74) in case of I-II VUR, 93% (n=92/99) in case of III VUR; 96% (n=44/46) in case of IV VUR; 100% (n=9/9) in case of V VUR (p-value: 0.083). Despite not being statistically significant, the VUR resolution rate was higher for the "combined STING-HIT" technique, both after one (92%: n=110/119; versus 85%; n=62/73 versus 86%; n=31/36; p-value: 0.225) or two (98%: n=116/119; versus 95%; n=69/73 versus 94%; n=34/36; p-value: 0.469) endoscopic treatments.
Conclusion: The endoscopic approaches were highly successful for the treatment of VUR in children. The "combined STING-HIT" technique was a safe and effective procedure, being associated with the higher resolution rate.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227862 | PMC |
| http://dx.doi.org/10.2147/RRU.S467018 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ultrasound elastographic evaluation of renal parenchyma in pediatric patients with vesicoureteral reflux.
J Pediatr Urol
August 2025
Gaziantep University Medical Faculty, Department of Urology, Gaziantep, Turkey. Electronic address:
Objective: The most common chronic complication of vesicoureteral reflux (VUR) is the presence of renal scarring and dimercapto succinic acid (DMSA) renal scan is utilized for its detection. In this study, we have aimed to assess whether shear wave speed (SWS) differs between normal and refluxing kidneys.
Materials And Method: Fifty pediatric VUR patients and 21 healthy children with available DMSA obtained within the previous year were included in the study.
Biplanar extra- and trans-peritoneal ureterocutaneostomy by laparoscopy (BETUL).
J Pediatr Urol
August 2025
Ondokuz Mayıs University, Department of Pediatric Surgery, Ondokuz Mayıs Üniversitesi, Kurupelit Kampüsü, Atakum, 55270, Samsun, Turkey. Electronic address:
Introduction: Although rare, incontinent diversions still has a place in the management of challenging conditions. Ureterocutaneostomy (in refluxing or non-refluxing moieties) is a viable option for relief of obstruction. It can be performed open or laaproscopically.
View Article and Find Full Text PDFPseudomonas UTI Masquerading as Neonatal Jaundice: A Case Report.
Indian J Nephrol
July 2024
Department of Pediatrics, All India Institute of Medical Sciences, Kalyani, West Bengal, India.
The pathological jaundice in neonates develops due to hematological, infectious, surgical causes. We present an interesting case of persistent neonatal hyperbilirubinemia, who was diagnosed to have urinary tract infection (UTI) and effectively managed. Unexplained persistent neonatal jaundice, poor response to phototherapy, and higher rebound total serum bilirubin levels should be evaluated for UTI.
View Article and Find Full Text PDFUreteral stent in ureteroneocystostomy for vesicoureteral reflux: Analysis of the data from National Surgical Quality Improvement Program-Pediatrics.
Can Urol Assoc J
August 2025
Department of Urologic Sciences, University of British Columbia, British Columbia Children's Hospital, Vancouver, BC, Canada.
Introduction: We aimed to assess the association between stent placement during ureteral reimplantation for vesicoureteral reflux (VUR) and short-term postoperative outcomes.
Methods: We conducted a retrospective analysis of National Surgical Quality Improvement Program-Pediatrics (NSQIP-P). Independent variables included stent placement, age, sex, urologic comorbidity, prior VUR procedures, severity of reflux, preoperative urinary tract infections (UTIs), American Society of Anesthesiologists (ASA) classification, and operative approach.
EFFICACY OF ELECTROMYOGRAPHIC BIOFEEDBACK FOR DYSFUNCTIONAL VOIDING IN CHILDREN AND ADOLESCENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED TRIALS.
Urology
August 2025
UNIVERSIDADE FEDERAL DE SÂO PAULO - ESCOLA PAULISTA DE MEDICINA - POSTGRADUATE COURSE IN TRANSLATIONAL MEDICINE. Electronic address:
Objective: To assess the efficacy of electromyographic biofeedback (EMG-BF) in the treatment of dysfunctional voiding (DV) in children and adolescents by synthesizing evidence from randomized controlled trials.
Methods: We conducted a systematic review and meta-analysis of randomized and controlled trials evaluating EMG-BF therapy in pediatric patients diagnosed with DV. Searches were performed across seven databases (Cochrane Central Register of Controlled Trials, PubMed/MEDLINE, EMBASE, Scopus, Web of Science, Livivo, and LILACS) up to January 2025.