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http://dx.doi.org/10.1002/cac2.12589 | DOI Listing |
Int Dent J
September 2025
Department of Periodontology, Oral Medicine and Oral Surgery, Institute for Dental and Craniofacial Sciences, Charité-University Medicine Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Department of Conservati
Introduction And Aims: Artificial intelligence (AI) is transforming dental care by enhancing diagnostic accuracy, efficiency, and patient experience. This study aimed to assess dental patients' acceptance, perceptions, and concerns regarding AI-powered diagnosis using the Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) framework through structural equation modelling (SEM).
Methods: A cross-sectional study was conducted among dental patients at King Saud University Dental Hospital, Riyadh.
Curr Opin Hematol
August 2025
Hematopoietic Stem Cell Transplantation Program. Hematology Department Pontificia Universidad Católica de Chile Red de Salud Christus UC.
Purpose Of Review: Acute myeloid leukemia (AML) is a biologically diverse disease that has undergone significant transformation in recent years. The rapid pace of discovery in molecular genetics, disease classification, and therapeutic development has reshaped how we approach diagnosis and treatment. This review aims to provide a timely and relevant synthesis of these advances, offering clinicians and researchers an updated perspective on AML as of 2025.
View Article and Find Full Text PDFCurr Med Chem
September 2025
State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, 3rd Section of Ren Min Nan Rd., Chengdu, 610041, China.
Introduction: Current osteoporosis medications often prove ineffective for various reasons. Alongside optimizing available agents, new genetic targets should be proposed for drug development. Mendelian randomization (MR) may resolve throughput and confounding issues in traditional observational studies for druggable targets.
View Article and Find Full Text PDFEur Rev Med Pharmacol Sci
August 2025
Private Practice.
Unlabelled: OBJECTIVE: In this multicenter study, we assessed the effectiveness of a novel autologous bone substitute obtained directly from the processing of extracted teeth. A total of 34 consecutive tooth grafting procedures were performed. MATERIALS AND METHODS: Immediately following atraumatic extraction for restorative or endodontic purposes, the bone defect was filled and covered with an Osseoguard© membrane, using autologous material derived from the extracted tooth.
View Article and Find Full Text PDFJ Immunol
September 2025
Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, United States.
Transforming growth factor beta (TGFβ) is an immunosuppressive cytokine that is overexpressed in tumor microenvironments. We have shown that CD8+ T cells with genetic ablation of the TGFβ type I receptor, Alk5 (CD8ΔALK5), were more sensitive to αCD3 stimulation resulting in enhanced proliferation and cytokine production. Based on these data, we hypothesized that TGFβ impaired T-cell receptor (TCR) signaling.
View Article and Find Full Text PDF