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Article Abstract

Case: A healthy, 19-year-old woman was incidentally found to have a large, destructive tumor of T11 without neurologic symptoms. Biopsy demonstrated fibrocartilaginous mesenchymoma (FCM). The patient was treated with resection including subtotal corpectomy and T8-L1 fusion with use of cage and allograft strut construct. The patient remained without recurrence over 3 years of follow-up.

Conclusion: FCM arising from the spine is a rare tumor, of which this is the sixth report. FCM affects primarily young adults and is benign but locally aggressive, requiring complete excision to prevent recurrence.

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http://dx.doi.org/10.2106/JBJS.CC.23.00648DOI Listing

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Article Synopsis
  • - A 19-year-old woman was found to have a large tumor at the T11 spine, identified as fibrocartilaginous mesenchymoma (FCM) after a biopsy, despite having no neurological symptoms.
  • - She underwent surgical treatment that involved removing most of her spine vertebra (subtotal corpectomy) and a fusion from T8 to L1 using a cage and allograft strut.
  • - FCM is a rare, locally aggressive tumor that primarily affects young adults and requires complete removal to prevent recurrence; this case marks only the sixth known instance.
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To investigate the clinical, radiological, histological and molecular features and the differential diagnosis of fibrocartilaginous mesenchymoma (FM). Four cases of FM diagnosed in the Department of Pathology, the Sixth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine from 2020 to 2022 were analyzed. Related literature was also reviewed.

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Fibrocartilaginous mesenchymoma (FM) is a rare bone tumor mimicking other fibrocartilaginous lesions on imaging and histologically. Hence, it is difficult to diagnose this entity especially on small biopsies. In this article, we report a case of FM mimicking desmoplastic fibroma on biopsy.

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Fibrocartilaginous mesenchymoma with an unusual location in the rib.

J Pathol Transl Med

January 2021

Department of Pathology, Kosin University Gospel Hospital, Busan, Korea.

Fibrocartilaginous mesenchymoma is a rare bone tumor, with fewer than 35 cases reported in the literature since 1984. This tumor usually occurs in the long bones of children and adolescents. In the current case, the tumor affected a rib.

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