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Article Abstract
Background: Few studies have compared the associations between long-term exposures to particulate matters (aerodynamic diameter ≤1, ≤2.5 and ≤10 µm: PM, PM and PM, respectively) and asthma and asthma-related respiratory symptoms. The objective of the present study was to compare the strength of the aforementioned associations in middle-aged and elderly adults.
Methods: We calculated the mean 722-day personal exposure estimates of PM, PM and PM at 1 km×1 km spatial resolution between 2013 and 2019 at individual levels from China High Air Pollutants (CHAP) datasets. Using logistic regression models, we presented the associations as odds ratios and 95% confidence intervals, for each interquartile range (IQR) increase in PM/PM/PM concentration. Asthma denoted a self-reported history of physician-diagnosed asthma or wheezing in the preceding 12 months.
Results: We included 7371 participants in COPD surveillance from Guangdong, China. Each IQR increase in PM, PM and PM was associated with a greater odds (OR (95% CI)) of asthma (PM: 1.22 (1.02-1.45); PM: 1.24 (1.04-1.48); PM: 1.30 (1.07-1.57)), wheeze (PM: 1.27 (1.11-1.44); PM: 1.30 (1.14-1.48); PM: 1.34 (1.17-1.55)), persistent cough (PM: 1.33 (1.06-1.66); PM: 1.36 (1.09-1.71); PM: 1.31 (1.02-1.68)) and dyspnoea (PM: 2.10 (1.84-2.41); PM: 2.17 (1.90-2.48); PM: 2.29 (1.96-2.66)). Sensitivity analysis results were robust after excluding individuals with a family history of allergy. Associations of PM, PM and PM with asthma and asthma-related respiratory symptoms were slightly stronger in males.
Conclusion: Long-term exposure to PM is associated with increased risks of asthma and asthma-related respiratory symptoms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11215765 | PMC |
| http://dx.doi.org/10.1183/23120541.00972-2023 | DOI Listing |
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