Nutritional Profile, Disease Severity, and Quality of Life of Patients with Inflammatory Bowel Disease: A Case-Control Study.

Introduction: Diet is thought to play an important role in the clinical course and quality of life (QOL) of patients with inflammatory bowel disease (IBD). However, dietary habits of patients with IBD are still unknown. This case-control study aims to compare the dietary habits of patients with IBD to healthy controls and evaluate differences in disease severity and QOL.

Materials And Methods: Food frequency, severity scores using the Harvey-Bradshaw and Ulcerative colitis activity index, and QOL were assessed using online questionnaires. Dietary habits were compared for patients with active disease and remission and for those with low QOL (LQOL) and high QOL (HQOL).

Results: We recruited 61 patients with IBD and 101 controls. Significance was set at = 0.05. Controls consumed significantly more daily calories (2546 vs. 1641, = 0.001). However, patients with IBD consumed a higher percentage of carbohydrates (50% vs. 45%, = 0.001), more red meat ( = 0.024), and less fiber, sucrose, and lactose ( = 0.001, 0.001, and 0.036). Patients with active disease had higher lipid intake, lower protein intake, and lower QOL (47 vs. 58, = 0.001). Dietary differences between LQOL and HQOL mirrored those between active disease and remission.

Conclusion: This study is the first to provide valuable insights into the nutritional profile of Lebanese patients with IBD.