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Background: People with intellectual and sensory or sensory-motor disabilities tend to have problems performing multistep tasks. To alleviate their problems, technological solutions have been developed that provide task-step instructions. Instructions are generally delivered at people's request (eg, as they touch an area of a computer or tablet screen) or automatically, at preset intervals.
Objective: This study carried out a preliminary assessment of a new tablet-based technology system that presented task-step instructions when participants with intellectual and sensory disabilities walked close to the tablet (ie, did not require participants to perform fine motor responses on the tablet screen).
Methods: The system entailed a tablet and a wireless camera and was programmed to present instructions when participants approached the tablet, that is, when the camera positioned in front of the tablet detected them. Two instructions were available for each task step. One instruction concerned the object(s) that the participants were to collect, and the other instruction concerned the "where" and "how" the object(s) collected would need to be used. For 3 of the six participants, the two instructions were presented in succession, with the second instruction presented once the required object(s) had been collected. For the other 3 participants, the two instructions were presented simultaneously. Instructions consisted of pictorial representations combined with brief verbal phrases. The impact of the system was assessed for each of the 2 groups of participants using a nonconcurrent multiple baseline design across individuals.
Results: All participants were successful in using the system. Their mean frequency of correct task steps was close to or above 11.5 for tasks including 12 steps. Their level of correct performance tended to be much lower during the baseline phase when they were to receive the task-step instructions from a regular tablet through scrolling responses.
Conclusions: The findings, which need to be interpreted with caution given the preliminary nature of the study, suggest that the new tablet-based technology system might be useful for helping people with intellectual and sensory disabilities perform multistep tasks.
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http://dx.doi.org/10.2196/59315 | DOI Listing |
JAMA Netw Open
September 2025
Social and Behavioral Sciences Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Importance: Higher intellectual abilities have been associated with lower mortality risk in several longitudinal cohort studies. However, these studies did not fully account for early life contextual factors or test whether the beneficial associations between higher neurocognitive functioning and mortality extend to children exposed to early adversity.
Objective: To explore how the associations of child neurocognition with mortality changed according to the patterns of adversity children experienced.
J Health Serv Res Policy
September 2025
Department of Health and Society, University of Toronto Scarborough, Toronto, ON, Canada.
ObjectivesTo (1) understand the challenges and benefits of providing pregnancy care to people with disabilities and (2) identify strategies to address challenges, from the perspectives of health care and social service providers and decision-makers.MethodsWe undertook a qualitative descriptive study in Ontario, Canada, of 31 health care and social service providers and decision-makers. Participants completed semi-structured interviews about their education, training, and clinical or administrative experience working with pregnant and/or parenting people with physical, sensory, and intellectual or developmental disabilities, including challenges and benefits in pregnancy care provision, programming, and policies, as well as their recommendations to improve care.
View Article and Find Full Text PDFCurr Biol
August 2025
Department of Psychology, The University of Chicago, Chicago, IL 60637, USA; Institute for Mind and Biology, The University of Chicago, Chicago, IL 60637, USA.
Working memory (WM) is a core component of intellectual ability. Traditional behavioral accounts have argued that there remain distinct memory systems based on the type and sensory modality of information being stored. However, more recent work has provided evidence for a class of neural activity that indexes the number of visual items stored in a content-independent fashion.
View Article and Find Full Text PDFNeurobiol Dis
September 2025
Institute of Physiology of the Czech Academy of Sciences; Prague, Czech Republic.. Electronic address:
The TRPC5 (Transient Receptor Potential Canonical 5) receptor, which is highly expressed in the brain, kidney, and sensory neurons, is emerging as a pharmacological target due to its involvement in renal physiology, pain, metabolic homeostasis, and various neurodevelopmental disorders. The recently identified R175C mutation associated with intellectual disability and autism spectrum disorders has supported the critical importance of TRPC5 for central nervous system function. Compared to other neuronal TRPs, TRPC5 remains understudied, with its activation mechanisms not well understood.
View Article and Find Full Text PDFBr J Pain
August 2025
School of Health and Social Wellbeing, University of the West of England, Bristol, UK.
Introduction: Sensory discrimination training has demonstrated improvements in two-point discrimination and pain reduction in people with chronic pain. We tested the feasibility and acceptability of a novel Sensory Training System (STS) device in the homes of people with Type 1 Complex Regional Pain Syndrome (CRPS).
Methods: Participants meeting CRPS diagnostic criteria were invited to use the STS for a minimum of 30 minutes per day for 30 days.