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http://dx.doi.org/10.1016/j.jaad.2024.05.078 | DOI Listing |
Jpn J Ophthalmol
September 2025
Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto City, Kyoto Prefecture, 606-8507, Japan.
Purpose: To identify predictors of the 2-year best-corrected visual acuity (BCVA) after subretinal tissue plasminogen activator (tPA) injection for massive submacular hemorrhage (SMH) complicating neovascular age-related macular degeneration (nAMD).
Study Design: A prospective, observational study.
Methods: This study included consecutive eyes with massive SMH and nAMD that underwent vitrectomy with subretinal tPA injection and follow-up for 2 years.
Diabetes Ther
September 2025
Department of Diabetes and Endocrinology, Guy's and St Thomas' NHS Trust, London, UK.
Introduction: This post hoc analysis of an A Toujeo Observational Study (ATOS) aims to evaluate the real-world effectiveness and safety of insulin glargine 300 U/ml (Gla-300) in high-risk subgroups of insulin-naïve people with type 2 diabetes (PwT2D) from multiple geographical regions (Asia, the Middle East, North Africa, Latin America, and Eastern Europe).
Methods: In these post hoc analyses of ATOS, a real-world, 12-month, prospective study included 4422 insulin-naïve adults (age ≥ 18 years) with type 2 diabetes (T2D) uncontrolled (HbA > 7% and ≤ 11%) on one or more oral antidiabetic drugs (OADs) who initiated Gla-300 treatment as per routine practice. Primary and secondary endpoints were studied according to renal impairment (RI) status (without or with) and age group (≥ 70 years).
Cell Tissue Bank
September 2025
Department of Ophthalmology and Visual Sciences, McGill University, Montreal, Canada.
To summarize the evidence examining the outcomes of Descemet membrane endothelial keratoplasty (DMEK) using eye bank pre-stripped versus surgeon prepared grafts. Systematic review and meta-analysis. This study was conducted following the preferred reporting items for systematic reviews and meta-analyses consensus statement (PROSPERO ID: CRD42023457120).
View Article and Find Full Text PDFJ Intensive Care Med
September 2025
Medical Intensive Care Unit, 108 Military Central Hospital, Hanoi, Vietnam.
Background: Bedside ultrasound is increasingly utilized to assess muscle mass in critically ill patients, providing a noninvasive and real-time tool for early risk stratification. Muscle wasting is known to be associated with adverse outcomes in septic shock, but its prognostic value using ultrasound in this population remains underexplored. This study aimed to investigate the association between changes in rectus femoris cross-sectional area (CSA), assessed by bedside ultrasound, and 28-day mortality in patients with septic shock.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.