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Background: Three-dimensional (3D) printing has emerged as a promising new technology for the development of surgical prosthetics. Research in orthopedic surgery has demonstrated that using 3D printed customized prosthetics results in more precise implant placements and better patient outcomes. However, there has been little research on implementing customized 3D printed prosthetics in otolaryngology. The program sought to determine whether computed tomography (CT) serves as feasible templates to construct 3D printed palatal obturator prosthetics for defects in patients who have been treated for head and neck cancers.
Observations: A retrospective review of patients with palatal defects was conducted and identified 1 patient with high quality CTs compatible with 3D modeling. CTs of the patient's craniofacial anatomy were used to develop a 3D model and a Formlabs 3B+ printer printed the palatal prosthetic. We successfully developed and produced an individualized prosthetic using CTs from a veteran with head and neck deformities caused by cancer treatment who was previously treated at the Veterans Affairs Palo Alto Health Care System. This project was successful in printing patient-specific implants using CT reproductions of the patient's craniofacial anatomy, particularly of the palate. The program was a proof of concept and the implant we created was not used on the patient.
Conclusions: Customized 3D printed implants may allow otolaryngologists to enhance the performance and efficiency of surgeries and better rehabilitate and reconstruct craniofacial deformities to restore appearance and function to patients. Additional research will strive to enhance the therapeutic potential of these prosthetics to serve as low-cost, patient-specific implants.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132111 | PMC |
http://dx.doi.org/10.12788/fp.0464 | DOI Listing |
Eur J Ophthalmol
September 2025
vEyes NPO, vEyes Lab, Milo, Italy.
PurposeTo introduce, describe and validate a novel, 3D-printed portable slit lamp system integrated with a macro lens-equipped smartphone, providing clinicians with a quick, easy, and effective method for obtaining high-quality clinical images.Materials and MethodsA 3D-printed portable slit lamp was developed, comprising a warm white LED light pen housed in a custom case with a biconvex lens focusing light through a 0.4 mm slit.
View Article and Find Full Text PDFNanomicro Lett
September 2025
Department of Mechanical, Aerospace & Biomedical Engineering, University of Tennessee, Knoxville, Knoxville, TN, 37996, USA.
3D printing, as a versatile additive manufacturing technique, offers high design flexibility, rapid prototyping, minimal material waste, and the capability to fabricate complex, customized geometries. These attributes make it particularly well-suited for low-temperature hydrogen electrochemical conversion devices-specifically, proton exchange membrane fuel cells, proton exchange membrane electrolyzer cells, anion exchange membrane electrolyzer cells, and alkaline electrolyzers-which demand finely structured components such as catalyst layers, gas diffusion layers, electrodes, porous transport layers, and bipolar plates. This review provides a focused and critical summary of the current progress in applying 3D printing technologies to these key components.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
Department of Traditional Chinese Medicine Rehabilitation, Jiangbei Branch of The First Hospital Affiliated to Army Medical University (Third Military Medical University), Chongqing, China.
Background: Complex interbody fusion remains challenging, while traditional surgical instruments are not suitable for complex spinal deformities. Porous tantalum (Ta) has excellent osteogenic properties, but there is currently a lack of research on its application in cervical thoracic interbody fusion.
Objective: To introduce the application of selective electron beam melting (SEBM) 3D printing technology in customized porous Ta vertebral fusion implants and evaluate its mid-term clinical efficacy in complex cervical thoracic fusion surgery.
Front Bioeng Biotechnol
August 2025
The Third Department of Orthopedic Surgery, Fuxin Mining General Hospital of Liaoning Health Industry Group, Liaoning, China.
Tendon/ligament (T/L) injuries sustained during motion are highly prevalent and severely impact athletes' careers and quality of life. Current treatments, including autografts, allografts, and synthetic ligaments, have limitations such as donor site morbidity, immune rejection, and biomechanical mismatch, especially under dynamic loading conditions encountered in motion. 3D bioprinting offers a revolutionary approach for constructing patient-specific T/L grafts.
View Article and Find Full Text PDFMater Today Bio
October 2025
Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Organ-on-a-chip (OoC) systems can simulate the key functions of human organs, combining microfluidics, cell culture, and biomaterials. 3D printing can be integrated into these technologies to facilitate the construction of OoC models. The high precision and layer-by-layer fabrication process of 3D printing not only enables the creation of complex structures for the microfluidic chip but also improves the cellular microenvironment within the chip by harnessing bioinks for 3D bioprinting.
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