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The precipitation-hardenable nickel-based superalloy Rene 41 exhibits remarkable mechanical characteristics and high corrosion resistance at high temperatures, properties that allow it to be used in high-end applications. This research paper presents findings on the influence of thermal shocks on its microstructure, hardness, and thermal diffusivity at temperatures between 700 and 1000 °C. Solar energy was used for cyclic thermal shock tests. The samples were characterized using microhardness measurements, optical microscopic analysis, scanning electron microscopy coupled with EDS elemental chemical analysis, X-ray diffraction, and flash thermal diffusivity measurements. Structural transformations and the variation of properties were observed with an increase in the number of shocks applied at the same temperature and with temperature variation for the same number of thermal shocks.
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http://dx.doi.org/10.3390/ma17102262 | DOI Listing |
Adv Sci (Weinh)
September 2025
Department of Biomedical Engineering, College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, 210023, China.
Heat shock protein 70 (HSP70) represents a critical barrier to effective mild-temperature photothermal therapy (MPTT), limiting its clinical utility in aggressive cancers like triple-negative breast cancer (TNBC). While small interfering RNA (siRNA)-mediated HSP70 suppression offers a promising solution, optimal timing for this therapeutic combination remains unexplored. Here, it is demonstrated that precisely timed administration significantly enhances MPTT efficacy through systematic temporal characterization of HSP70 expression dynamics.
View Article and Find Full Text PDFFish Shellfish Immunol
September 2025
MOE Key Laboratory of Molecular Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China; Key Laboratory of Tropical Aquatic Germplasm of Hainan Province, Sanya Oceanographic Institution, Ocean University of China, Sanya, 572025, China. Electronic add
Functioning as molecular chaperones, heat shock proteins (HSPs) are rapidly upregulated under stress conditions, safeguarding cells against damage induced by heat, mechanical injury, and chemical agents. Despite their critical physiological roles, a comprehensive genome-wide characterization of HSP genes has been lacking for Sebastes schlegelii, a commercially important coastal benthic fish. In this study, we systematically identified the HSP gene family and analyzed its expression profiles.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
State Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou 311400, China.
As global climate change exacerbates extreme heat events, the interplay between heat stress and blast disease resistance in rice remains poorly understood. In this study, through integrated transcriptome profiling and systematic phenotyping of mutants in several thermosensory pathways, we identified HsfA1 as a positive regulator of heat priming-enhanced blast resistance in rice. Systematic analysis of microRNA (miRNA) dynamics, bioinformatics prediction, and RNA pull-down experiments revealed that , a temperature-responsive miRNA, directly suppresses the expression of by targeting the second exon of messenger RNA (mRNA).
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
Chemical Sciences and Engineering Division, Argonne National Laboratory, Lemont, IL, US.
The thermal decomposition of isopropanol was studied experimentally and theoretically with a view to isolate and directly measure rate coefficients for the dominant radical channel in this multi-channel process. Two complementary shock tube methods, laser schlieren densitomtery and H-atom atomic resonance absorption spectroscopy, were used to obtain rate coefficents for the C-C bond fission channel. The experimental ranges span temperatures from 1200-2100 K and pressures between 30-690 torr.
View Article and Find Full Text PDFSensors (Basel)
August 2025
School of Aerospace Engineering, Xiamen University, Xiamen 361005, China.
Aerospace engines and hypersonic vehicles, among other high-temperature components, often operate in environments characterized by temperatures exceeding 1000 °C and high-speed airflow impacts, resulting in severe thermal erosion conditions. Coaxial thermocouples (CTs), with their unique self-eroding characteristic, are particularly well suited for use in such extreme environments. However, fabricating high-temperature electrical insulation layers for coaxial thermocouples remains challenging.
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