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Retinal disorders pose a serious threat to world healthcare because they frequently result in visual loss or impairment. For retinal disorders to be diagnosed precisely, treated individually, and detected early, deep learning is a necessary subset of artificial intelligence. This paper provides a complete approach to improve the accuracy and reliability of retinal disease identification using images from OCT (Retinal Optical Coherence Tomography). The Hybrid Model GIGT, which combines Generative Adversarial Networks (GANs), Inception, and Game Theory, is a novel method for diagnosing retinal diseases using OCT pictures. This technique, which is carried out in Python, includes preprocessing images, feature extraction, GAN classification, and a game-theoretic examination. Resizing, grayscale conversion, noise reduction using Gaussian filters, contrast enhancement using Contrast Limiting Adaptive Histogram Equalization (CLAHE), and edge recognition via the Canny technique are all part of the picture preparation step. These procedures set up the OCT pictures for efficient analysis. The Inception model is used for feature extraction, which enables the extraction of discriminative characteristics from the previously processed pictures. GANs are used for classification, which improves accuracy and resilience by adding a strategic and dynamic aspect to the diagnostic process. Additionally, a game-theoretic analysis is utilized to evaluate the security and dependability of the model in the face of hostile attacks. Strategic analysis and deep learning work together to provide a potent diagnostic tool. This suggested model's remarkable 98.2% accuracy rate shows how this method has the potential to improve the detection of retinal diseases, improve patient outcomes, and address the worldwide issue of visual impairment.
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http://dx.doi.org/10.3233/XST-240027 | DOI Listing |
PLoS One
September 2025
HUN-REN Centre for Ecological Research, Institute of Evolution, Budapest, Hungary.
We develop a model that integrates evolutionary matrix game theory with Mendelian genetics. Within this framework, we define the genotype dynamics that describes how the frequencies of genotypes change in sexual diploid populations. We show that our formal definition of evolutionary stability for genotype distributions implies the stability of the corresponding interior equilibrium point in the genotype dynamics.
View Article and Find Full Text PDFMol Syst Biol
September 2025
TBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France.
Overflow metabolism refers to the widespread phenomenon of cells excreting metabolic by-products into their environment. Although overflow is observed in virtually all living organisms, it has been studied independently and given different names in different species. This review highlights emerging evidence that overflow metabolism is governed by common principles in prokaryotic and eukaryotic organisms.
View Article and Find Full Text PDFPLoS One
September 2025
School of Information Management and Engineering, Shanghai University of Finance and Economics, Shanghai, PR China.
E-tailers such as Amazon and Tmall can accurately recognize consumer interest in product categories and grasp current consumer trends through product recommendation algorithms and data-driven analysis. In this study, we develop a game-theoretic model to investigate the encroachment and information sharing decisions considering data-driven marketing (DDM). Our outcomes reveal that the manufacturer has the incentive to reduce the wholesale price to incentivize the e-tailer to increase the DDM effort when the spillover effect is high and the marginal cost is low.
View Article and Find Full Text PDFJ Exp Anal Behav
September 2025
Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Cooperation involves an individual's choice that benefits both themself and others -in contrast to selfishness, which benefits the individual only-and has been suggested to be more likely when the benefit to others, discounted as a function of their social distance (i.e., social discounting), exceeds the undiscounted cost to the cooperator.
View Article and Find Full Text PDFAnn Pharm Fr
September 2025
Nantes Université, CHU Nantes, Pharmacie, F-44000 Nantes, France; Nantes Université, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, F-44000 Nantes, France.
Objectives: Patients with a jejunostomy use their tube daily in most cases, which exposes them to various complications. However, to our knowledge, the current literature is limited regarding available educational interventions or tools for these patients, and no specific competency framework for surgical jejunostomy has been developed yet. This project aimed to develop a unique and adapted competency framework for surgical jejunostomy patients through a multiprofessional and consensus-driven approach and to create a fun educational tool based on this framework to promote an effective educational approach.
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