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http://dx.doi.org/10.1016/j.jvscit.2024.101497 | DOI Listing |
Port J Card Thorac Vasc Surg
August 2025
Department of Angiology and Vascular Surgery, Hospital Beatriz Ângelo, Portugal.
Objective: The purpose of this article was to evaluate the clinical impact of diabetic foot ulcer (DFU) severity in patients with chronic limb-threatening ischemia (CLTI) who underwent distal open revascularization.
Methods: This study included a single-center retrospective analysis of diabetic patients with CLTI who underwent distal revascularization between January 2012 and December 2019. The sample was divided into two groups according to DFU severity; group 1 was defined if observed Wound grade ≥ 2 and Infection grade ≥ 1 and group 2 was defined if observed Wound grade < 2 and Infection grade < 1, according to Wound, Ischemia, and foot Infection (WIfI) classification.
J Endovasc Ther
August 2025
Vascular and Interventional Physicians, Gainesville, FL, USA.
The evolution from critical limb ischemia to chronic limb-threatening ischemia (CLTI) necessitates a reevaluation of clinical trial endpoints. Traditional measures like hemodynamic indices and lesion patency inadequately reflect CLTI complexity or patient-centered outcomes. This article explores the limitations of conventional endpoints and proposes a modified definition of clinically-driven target lesion (TL) revascularization (CD-TLR) that addresses inflow, TL, and outflow disease.
View Article and Find Full Text PDFJ Vasc Surg
July 2025
Department of Cardiology, Caress Memorial Hospital, Sapporo, Japan.
Objective: In patients with chronic limb-threatening ischemia (CLTI), the Global Limb Anatomical Staging System (GLASS) P2 modifier, defined by the absence of a target artery crossing the ankle and lack of a suitable pedal or plantar artery, indicates a no-option anatomic pattern. Although several studies have reported successful endovascular therapy (EVT) in such patients, EVT outcome predictors in this high-risk population remain unclear. This study aimed to identify factors contributing to procedural failure in patients with the GLASS P2 modifier undergoing EVT.
View Article and Find Full Text PDFVasc Health Risk Manag
July 2025
Cardiology Division, Midwest Cardiovascular Research Foundation, Davenport, IA, USA.
Background: Intravascular Ultrasound (IVUS) has been shown in smaller studies to improve outcomes when used to guide infrainguinal peripheral arterial interventions. The iDissection series of studies were conducted to determine the presence of dissections with various prepping devices in femoropopliteal and infrapopliteal arteries. The impact of IVUS-directed treatment on the long-term outcomes in these patients remains unclear.
View Article and Find Full Text PDFJ Soc Cardiovasc Angiogr Interv
March 2025
Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.
Background: Data supporting the use of intravascular ultrasound (IVUS) in aortoiliac and femoropopliteal endovascular intervention are becoming increasingly robust, but data in the infrapopliteal circulation remain limited. The aim of this study was to evaluate the association between IVUS use and 1-year outcomes after infrapopliteal intervention.
Methods: All infrapopliteal endovascular interventions that occurred between 2018-2021 at a single academic medical center were retrospectively reviewed.