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University education is a leading source of information for dental practitioners. Particular emphasis should be given to determining the extent to which students acquire positive knowledge, attitudes, and practices (KAP) and positive metacompetences beyond the scope of each studied dental discipline. We performed a cross-sectional questionnaire-based study among dentistry students from Romania to assess self-perceived risk of infectious diseases and their KAP on topics related to infectious disease prevention. The surveyed students presented good knowledge regarding personal protective equipment (PPE), and their PPE practices significantly correlated with the perceived usefulness of PPE. Only 45.1% correctly recognized all vaccine-preventable diseases (VPDs), but knowledge regarding VPDs significantly improved with increasing year of study (τ = 0.298, = 0.001), confirming a positive education effect. Awareness regarding the need for screening for bloodborne viruses is poor; the majority of students had never performed a test for hepatitis C virus infection (HCV) (59.4%) or for human immunodeficiency virus (HIV) infection (60.4%). Furthermore, most respondents incorrectly considered themselves at high or very high risk of acquiring BBV, and perceived risk was inversely correlated with willingness to treat patients with hepatitis B virus (HBV) infection (τ = -0.214, = 0.018), HCV infection (τ = -0.234, = 0.013), or HIV infection (τ = -0.242, = 0.006). This led to 3.0% of respondents stating that they would hypothetically deny dental treatment to a patient with HBV infection, 5.0% for HCV infection, and 10.9% for HIV infection, the proportion being significantly higher for HIV (z = -2.2, = 0.026). In conclusion, better knowledge is needed among dental students regarding their own vaccination history, screening for bloodborne viruses, accurate estimates for their risk of acquiring bloodborne viruses during routine dental practice, and the existence of post-exposure measures following occupational exposure. Improving student knowledge and awareness could translate into a higher willingness to treat patients with chronic viral infections and into a safer and more inclusive dental practice. We propose an adaptation to the university curriculum to cover these key areas for targeted focus to empower future dental practitioners and to facilitate the improvement of across-discipline metacompetences for infection prevention and control.
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http://dx.doi.org/10.3390/dj12040097 | DOI Listing |
J Assoc Res Otolaryngol
September 2025
Biological Sciences Platform, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, 2075 Bayview Ave., Room M1 102, Toronto, ON, M4N 3M5, Canada.
Purpose: Delivery of therapeutics to the inner ear is complicated by their inaccessible location and the presence of the blood-labyrinth barrier that restricts most blood-borne compounds from entering the inner ear. This study addresses the challenge of optimal delivery in treating inner ear disease, focusing on magnetic targeting gene therapy using adeno-associated virus (AAV).
Methods: The investigation explores three AAV serotypes (AAV2 Quad Mut, AAV2 pANC80L65, and AAV9 PHP.
Health Expect
October 2025
Centre for Social Research in Health, UNSW Sydney, Sydney, New South Wales, Australia.
Background: People from culturally and linguistically diverse (CALD) backgrounds who are living in high-income countries, are disproportionately impacted by blood-borne viruses and sexually transmissible infections (BBVs/STIs). Despite this, many do not engage with available preventive and treatment services due to a range of patient, provider and systems level barriers that make patient engagement challenging. This study explores ways to make healthcare services more acceptable and accessible to promote better health outcomes for Australian residents from CALD communities.
View Article and Find Full Text PDFBiotechnol J
September 2025
Department of Bioengineering, University of California, San Diego, La Jolla, California, USA.
Hepatitis C Virus (HCV) is a pervasive bloodborne virus and the leading cause of chronic liver disease and cancer. Thus, the development of an HCV vaccine is of great importance. Prior work has developed candidate vaccines, including more potent glycoengineered viral proteins and secreted forms of the E1E2 envelope heterodimer (sE1E2).
View Article and Find Full Text PDFCan Commun Dis Rep
July 2025
Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are sexually transmitted and blood-borne infections that Canada is committed to eliminate as public health concerns. Accurate epidemiological estimates require cross-sectional data as input. The objective of this study was to estimate the prevalence of present HBV infection (hepatitis B surface antigen-positive) and proportion aware of their infection, the vaccine-induced HBV immunity, the prevalence of HCV antibodies (anti-HCV-positive), the prevalence of present HCV infection (RNA-positive) and proportion aware of their infection, in the household population in Canada.
View Article and Find Full Text PDFInt J Med Inform
December 2025
Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham ME7 5NY, United Kingdom; Department of Public Health, York St John University, London, United Kingdom; School of Health and Care Management, Arden University, Arden House, Middlemarch Park, Coventry CV3 4FJ, United Kingdo
Introduction: Blood-borne viruses (BBVs) such as HIV, hepatitis B, and hepatitis C continue to pose serious public health concerns, particularly within emergency departments (EDs), where patient volume and turnover are high. While opt-out testing strategies, where individuals are tested unless they specifically decline, have shown effectiveness in increasing diagnosis rates, their adoption in EDs is limited by challenges such as inefficient workflows, data fragmentation, and suboptimal patient engagement.
Aim: This narrative review aims to explore the application of Artificial Intelligence (AI) in enhancing BBV opt-out testing in EDs, focusing on how AI can address current operational and clinical challenges while supporting ethical and equitable implementation.