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The measurement of Functional Reach Test (FRT) is a widely used assessment tool in various fields, including physical therapy, rehabilitation, and geriatrics. This test evaluates a person's balance, mobility, and functional ability to reach forward while maintaining stability. Recently, there has been a growing interest in utilizing sensor-based systems to objectively and accurately measure FRT results. This systematic review was performed in various scientific databases or publishers, including PubMed Central, IEEE Explore, Elsevier, Springer, the Multidisciplinary Digital Publishing Institute (MDPI), and the Association for Computing Machinery (ACM), and considered studies published between January 2017 and October 2022, related to methods for the automation of the measurement of the Functional Reach Test variables and results with sensors. Camera-based devices and motion-based sensors are used for Functional Reach Tests, with statistical models extracting meaningful information. Sensor-based systems offer several advantages over traditional manual measurement techniques, as they can provide objective and precise measurements of the reach distance, quantify postural sway, and capture additional parameters related to the movement.
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http://dx.doi.org/10.7717/peerj-cs.1823 | DOI Listing |
Environ Geochem Health
September 2025
Policy Research Center for Environment and Economy, Ministry of Ecology and Environment of the People's Republic of China, Beijing, 100101, China.
The behavior of polycyclic aromatic hydrocarbons (PAHs) released from tire road wear particles (TRWPs) in human digestive fluids may pose a significant risk to human health. However, the current understanding of the release pattern and influencing factors of PAHs from TRWPs is still insufficient. In this study, the release characteristics of PAHs from UV-aging TRWPs (ATRWPs) were systematically investigated by in vitro digestive simulation experiments, release kinetic model fitting and control variable experiments.
View Article and Find Full Text PDFInflamm Bowel Dis
September 2025
Gut Microbes and Health Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.
Background: Intestinal cells receive incoming signals from neighboring cells and microbial communities. Upstream signaling pathways transduce these signals to reach transcription factors (TFs) that regulate gene expression. In inflammatory bowel disease (IBD), most single nucleotide polymorphisms (SNPs) are in non-coding genomic regions containing TF binding sites.
View Article and Find Full Text PDFProtein Expr Purif
September 2025
Department of Brewing Engineering, Moutai Institute, Zunyi, 564507, People's Republic of China.
Aldehyde dehydrogenase 2 (ALDH2) plays a critical role in ethanol metabolism by converting toxic acetaldehyde to acetate. To investigate its functional mechanisms and potential therapeutic applications for alcohol-related diseases, heterologous expression of ALDH2 is essential. However, ALDH2 often forms inclusion bodies when expressed in Escherichia coli.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Planta Piloto de Procesos Industriales Microbiológicos (PROIMI-CONICET), Laboratorio de Biomateriales y Bioprocesos, Av. Belgrano y Pasaje Caseros, SM de Tucumán, 4000, Tucumán. R, Argentina; Universidad Nacional de Tucumán, Facultad de Bioquímica, Química y Farmacia. Laboratorio de Bioproceso
This study explores the use of plant-derived polysaccharides to develop bio-based films for food-packaging applications. A film-forming solution composed of Prosopis nigra biopolymer (PN-B), carboxymethyl cellulose (CMC), and glycerol was optimized by central composite design (CCD), resulting in two formulations: P1 and P11. The films were subsequently functionalized with silver nanoparticles (AgNPs) synthesized via chemical and biological routes.
View Article and Find Full Text PDFJ Pain
September 2025
Cyber-physical Health and Assistive Robotics Technologies Research Group, University of Nottingham, United Kingdom; School of Computer Science, University of Nottingham, Nottingham, United Kingdom.
Neck pain is among the most prevalent musculoskeletal conditions worldwide. The underlying cause mostly remains unidentified, classified as non-specific neck pain. Pain can alter movement patterns and physiological responses, suggesting that certain biomechanical and physiological changes may serve as objective biomarkers for non-specific neck pain.
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