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The accurate prediction of the future trajectories of traffic participants is crucial for enhancing the safety and decision-making capabilities of autonomous vehicles. Modeling social interactions among agents and revealing the inherent relationships is crucial for accurate trajectory prediction. In this context, we propose a goal-guided and interaction-aware state refinement graph attention network (SRGAT) for multi-agent trajectory prediction. This model effectively integrates high-precision map data and dynamic traffic states and captures long-term temporal dependencies through the Transformer network. Based on these dependencies, it generates multiple potential goals and Points of Interest (POIs). Through its dual-branch, multimodal prediction approach, the model not only proposes various plausible future trajectories associated with these POIs, but also rigorously assesses the confidence levels of each trajectory. This goal-oriented strategy enables SRGAT to accurately predict the future movement trajectories of other vehicles in complex traffic scenarios. Tested on the Argoverse and nuScenes datasets, SRGAT surpasses existing algorithms in key performance metrics by adeptly integrating past trajectories and current context. This goal-guided approach not only enhances long-term prediction accuracy, but also ensures its reliability, demonstrating a significant advancement in trajectory forecasting.
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http://dx.doi.org/10.3390/s24072065 | DOI Listing |
Brain
September 2025
Sorbonne University, Inserm U1127, CNRS UMR7225, UM75, Paris Brain Institute, Movement Investigation and Therapeutics Team, 75013 Paris, France.
Adolescence is frequently called the second brain maturation period. In Tourette disorder (TD), the clinical trajectory of tics and associated psychiatric co-morbidities vary significantly across individuals during the transition from adolescents to adulthood. In this study, we aimed to identify patterns of resting-state functional connectivity that differentiate adolescents with TD from their neurotypical peers, and to monitor symptom-specific functional changes over time.
View Article and Find Full Text PDFPLoS One
September 2025
Methodology and Analysis, Statistics Denmark, Copenhagen, Denmark.
Background: Previous studies have found paternal occupation, childhood intelligence, and educational attainment to be important predictors of socioeconomic status (SES) later in life. However, these factors only explain part of the variance in SES and thus, it is important to identify other predictors of SES and trajectories of influence from early childhood to adulthood.
Objectives: To analyze predictors of SES attainment during the life course from early childhood to midlife with special emphasis on identifying direct and indirect effects on midlife SES of early childhood, late childhood and young adult characteristics.
Bull Math Biol
September 2025
Department of Mathematics, Siena University, 515 Loudon Road, Loudonville, NY, 12211, USA.
Autonomous differential equation compartmental models hold broad utility in epidemiology and public health. However, these models typically cannot account explicitly for myriad factors that affect the trajectory of infectious diseases, with seasonal variations in host behavior and environmental conditions as noteworthy examples. Fortunately, using non-autonomous differential equation compartmental models can mitigate some of these deficiencies, as the inclusion of time-varying parameters can account for temporally varying factors.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: The pathophysiological changes driving incident kidney cancer remain unclear. This study aimed to identify protein biomarkers and underlying mechanisms using pre-diagnostic plasma proteomics.
Materials And Methods: Among 48,851 UK Biobank participants, 165 were diagnosed with kidney cancer, and 2,911 plasma proteins were analyzed.
J Pers
September 2025
Department of Developmental Psychology, Tilburg University, Tilburg, the Netherlands.
Objective: In recent decades, increased freedom of choice and advancements in fertility regulation have allowed individuals to follow different fertility paths. This greater autonomy provides room for personality traits to shape long-term fertility expectations, which in turn can be predictive of fertility outcomes. The present study investigates how Big Five personality traits are related to fertility expectations trajectories and outcomes.
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