Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Context: For some common thyroid-related conditions with high prevalence and long follow-up times, ChatGPT can be used to respond to common thyroid-related questions.
Objective: In this cross-sectional study, we assessed the ability of ChatGPT (version GPT-4.0) to provide accurate, comprehensive, compassionate, and satisfactory responses to common thyroid-related questions.
Methods: First, we obtained 28 thyroid-related questions from the Huayitong app, which together with the 2 interfering questions eventually formed 30 questions. Then, these questions were responded to by ChatGPT (on July 19, 2023), a junior specialist, and a senior specialist (on July 20, 2023) separately. Finally, 26 patients and 11 thyroid surgeons evaluated those responses on 4 dimensions: accuracy, comprehensiveness, compassion, and satisfaction.
Results: Among the 30 questions and responses, ChatGPT's speed of response was faster than that of the junior specialist (8.69 [7.53-9.48] vs 4.33 [4.05-4.60]; P < .001) and the senior specialist (8.69 [7.53-9.48] vs 4.22 [3.36-4.76]; P < .001). The word count of the ChatGPT's responses was greater than that of both the junior specialist (341.50 [301.00-384.25] vs 74.50 [51.75-84.75]; P < .001) and senior specialist (341.50 [301.00-384.25] vs 104.00 [63.75-177.75]; P < .001). ChatGPT received higher scores than the junior specialist and senior specialist in terms of accuracy, comprehensiveness, compassion, and satisfaction in responding to common thyroid-related questions.
Conclusion: ChatGPT performed better than a junior specialist and senior specialist in answering common thyroid-related questions, but further research is needed to validate the logical ability of the ChatGPT for complex thyroid questions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1210/clinem/dgae235 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bibliometrics in thyroid eye disease.
J Endocrinol Invest
August 2025
Molecular Thyroid Research Lab, Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, Mainz, 55101, Germany.
Purpose: Thyroid Eye Disease (TED) is the most common thyroid-related autoimmune inflammatory disorder. Despite a surge in TED-related publications over the past five years-matching the total output of the preceding sixteen years-a systematic bibliometric analysis remains absent. This study aims to systematically map the knowledge structure, research hotspots, and future trends in TED research.
View Article and Find Full Text PDFDiabetes, Celiac, and Thyroid-Related Autoantibodies in HLA Genotyped Ethiopian Children and Adolescents With Type 1 Diabetes: A Cross-Sectional Study.
Pediatr Diabetes
August 2025
Department of Clinical Sciences Malmö, Clinical Research Center, Lund University, Malmo, Sweden.
Autoantibodies against β-cell components in the pancreatic islets of Langerhans are characteristic of type 1 diabetes (T1D). The genetic and autoimmune determinants of type 1 diabetes (T1D) in Ethiopians are not yet thoroughly characterized, with studies indicating a lower occurrence of autoantibodies related to T1D compared to Caucasians. The study aimed to determine the occurrence of autoantibodies related to type 1 diabetes (T1D), celiac disease (CD), and autoimmune thyroid disease (AITD) in conjunction with Human Leukocyte Antigen (HLA) genotype in Ethiopian children and adolescents with T1D.
View Article and Find Full Text PDFPolycyclic aromatic hydrocarbons as potential risk factors for thyroid cancer: Epidemiological evidence of urinary metabolites and thyroid-related hormones.
Ecotoxicol Environ Saf
August 2025
School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address:
Thyroid cancer (TC) is a common malignant tumor of the endocrine system, with a markedly higher incidence in females. While radiation exposure remains the only proven exogenous risk factor, growing evidence implicates environmental pollutants in TC pathogenesis. Polycyclic aromatic hydrocarbons (PAHs) are endocrine-disrupting chemicals with well-established carcinogenicity.
View Article and Find Full Text PDFEffects of COVID-19 vaccination on irAEs and prognosis in lung cancer patients receive PD-(L)1 inhibitors.
Hum Vaccin Immunother
December 2025
Department of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, P. R. China.
The influence of COVID-19 vaccination on the efficacy and safety of immune checkpoint inhibitors (ICIs) in lung cancer treatment is not well understood. A cohort of 394 lung cancer patients treated with PD-1/PD-L1 inhibitors was analyzed. The incidence and types of irAEs were recorded, and the relationship between COVID-19 vaccination and progression-free survival (PFS) was assessed using univariate and multivariate analyses.
View Article and Find Full Text PDFPredictive factors for surgical interventions following intravenous glucocorticoid pulse therapy in active moderate-to-severe thyroid eye disease.
Hormones (Athens)
August 2025
Department of Endocrinology and Metabolic Diseases (including Division of Lipid Metabolism), European Reference Network on Rare Endocrine Diseases (ENDO-ERN), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Pla
Purpose: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves' disease (GD), driven by stimulatory thyrotropin receptor autoantibodies (TRAbs). Intravenous glucocorticoid pulse therapy (ivGC) is the first-line treatment for active moderate-to-severe TED. This retrospective cohort study aimed to identify predictive factors associated with treatment response in TED patients receiving ivGC therapy.
View Article and Find Full Text PDF