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The present study analyzed the microwave ablation of cancerous tumors located in six major cancer-prone organs and estimated the significance of input power and treatment time parameters in the apt positioning of the trocar into the tissue during microwave ablation. The present study has considered a three-dimensional two-compartment tumour-embedded tissue model. FEA based COMSOL Multiphysics software with inbuilt bioheat transfer, electromagnetic waves, heat transfer in solids and fluids, and laminar flow physics has been used to obtain the numerical results. Based on the mortality rates caused by cancer, the present study has considered six major organs affected by cancer, viz. lung, breast, stomach/gastric, liver, liver (with colon metastasis), and kidney for MWA analysis. The input power (100 W) and ablation times (4 minutes) with apt and inapt positioning of the trocar have been considered to compare the ablation volume of various cancerous tissues. The present study addresses one of the major problems clinicians face, i.e. the proper placement of the trocar due to poor imaging techniques and human error, resulting in incomplete tumor ablation and increased surgical procedures. The highest values of the ablation region have been observed for the liver, colon metastatic liver and breast cancerous tissues compared with other organs at the same operating conditions.
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http://dx.doi.org/10.1080/15368378.2024.2333802 | DOI Listing |
J Am Coll Surg
September 2025
Departments of Endocrine and General Surgery, Cleveland Clinic, Cleveland, OH.
Background: Although traditionally reserved for unresectable lesions, recent studies have provided evidence that in selected patients, microwave ablation (MWA) may provide similar oncologic outcomes compared to liver resection (LR). This study aimed to compare oncologic outcomes of patients with solitary small (<3 cm) colorectal liver metastasis (CRLM) undergoing LR vs laparoscopic MWA.
Study Design: This retrospective study included patients with a solitary CRLM <3cm treated with LR or MWA in three centers over 25-years.
Front Surg
August 2025
Breast Unit, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
Background: Breast cysts are more common in premenopausal women (61.5%), particularly between ages 35-50. Microwave ablation (MWA) has shown advantages in treating symptomatic cysts.
View Article and Find Full Text PDFGastro Hep Adv
June 2025
Division of Digestive Health and Liver Diseases, Department of Medicine, Miller School of Medicine at the University of Miami, Miami, Florida.
Cystic fibrosis, traditionally considered an infrequent childhood disease, has increased in incidence due to advances in screening, and therapies fortunately have advanced leading to increased survival rates. Cystic fibrosis liver disease (CFLD) is well-described in the pediatric population; however, with increased life expectancy rates, a second wave has been observed in adults and represents the third most common cause of death. Although complications of portal hypertension have been described in setting of CFLD, the development of hepatocellular carcinoma is an extremely rare event.
View Article and Find Full Text PDFJ Cancer Res Ther
September 2025
Department of Anesthesiology, Cardiovascular Institute, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Background: This study evaluated the efficacy and safety of esketamine plus dexmedetomidine for sedation and analgesia during computed tomography (CT)-guided lung tumor percutaneous microwave ablation (MWA).
Methods: Patients undergoing CT-guided percutaneous MWA of lung tumors were randomly divided into two groups: esketamine plus dexmedetomidine (Group E) and sufentanil plus dexmedetomidine (Group S). The patients' general information, mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation, respiratory rate (RR), partial pressure of end-tidal carbon dioxide, bispectral index, and Ramsay sedation score were recorded before anesthesia administration (T0), after dexmedetomidine loading dose (T1), during percutaneous puncture (T2), during ablation (T3), at the end of surgery (T4), and during recovery of consciousness (T5).
J Cancer Res Ther
September 2025
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Objective: This study aimed to evaluate the safety and efficacy of improved supine positioning components for lung tumor microwave ablation (MWA), with the goal of enhancing surgical efficiency, reducing complications, and improving patient experience.
Materials And Methods: One hundred patients undergoing MWA for lung tumors were randomly divided into two groups (n = 50 each): experimental (using improved components) and control (using traditional components). The improved positioning system included a high-density memory foam head pillow, lumbar and leg pillows, and adjustable fixing bands tailored to individual patient needs.