98%
921
2 minutes
20
Pyoderma gangrenosum (PG) is an autoinflammatory skin disease, and there is no definitive test or established criterion for its diagnosis yet. This report discusses a case of a 34-year-old male patient who presented with an unassuming lesion that quickly worsened with physical manipulation. He was eventually diagnosed with PG. This report highlights the importance of a quick and accurate diagnosis of PG to prevent the worsening of a PG wound and its associated morbidity. It provides a detailed description of the condition accompanied by images to further spread awareness of this rare diagnosis.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10910755 | PMC |
http://dx.doi.org/10.7759/cureus.53491 | DOI Listing |
J Eur Acad Dermatol Venereol
September 2025
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.
J Dermatolog Treat
December 2025
Department of Dermatology, Peking University Third Hospital, Beijing, China.
Aim: To evaluate the therapeutic efficacy and safety of the Janus kinase (JAK) inhibitor tofacitinib in the management of refractory perianal pyoderma gangrenosum (PG) under conditions of baseline immunosuppression and bone marrow suppression.
Methods: We present a 62-year-old male with a 4-month history of painful, progressive symmetrical perianal ulcerations diagnosed as PG, coexisting with condyloma acuminatum. The patient had a background of pure red cell aplasia and myasthenia gravis, and was undergoing chronic immunosuppressive therapy with prednisolone and tacrolimus.
Australas J Dermatol
September 2025
Concord Repatriation General Hospital, New South Wales, Australia.
J Am Acad Dermatol
September 2025
Department of Dermatology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
J Surg Res
September 2025
Nationwide Children's Hospital, Abigail Wexner Research Institute, Columbus, Ohio; Department of Plastic and Reconstructive Surgery, Nationwide Children's Hospital, Columbus, Ohio; Pediatric Comprehensive Wound Program, Nationwide Children's Hospital, Columbus, Ohio. Electronic address: Jenny.Barker
Introduction: Chronic wounds affect approximately 10.5 million individuals annually in the United States. Although recent studies have highlighted a surge in chronic wound cases among younger populations, the collective burden of pediatric chronic wounds remains understudied.
View Article and Find Full Text PDF