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Doppler echocardiography is a widely utilised non-invasive imaging modality for assessing the functionality of heart valves, including the mitral valve. Manual assessments of Doppler traces by clinicians introduce variability, prompting the need for automated solutions. This study introduces an innovative deep learning model for automated detection of peak velocity measurements from mitral inflow Doppler images, independent from Electrocardiogram information. A dataset of Doppler images annotated by multiple expert cardiologists was established, serving as a robust benchmark. The model leverages heatmap regression networks, achieving 96% detection accuracy. The model discrepancy with the expert consensus falls comfortably within the range of inter- and intra-observer variability in measuring Doppler peak velocities. The dataset and models are open-source, fostering further research and clinical application.
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http://dx.doi.org/10.1016/j.compbiomed.2024.108192 | DOI Listing |
Kardiologiia
September 2025
Second Affiliated Hospital of Chongqing Medical University, Department of Ultrasound Medicine.
Objective This research investigated the application of real-time, three-dimensional speckle tracking imaging (RT-3D-STI) to evaluate left atrial (LA) function in individuals suffering from hypertensive heart disease (HHD) and heart failure with preserved ejection fraction (HFpEF).Material and methods This retrospective study included 100 patients with HHD and HFpEF hospitalized from August 2023to June 2024 (HFpEF group). 100 healthy individuals undergoing physical examinations comprised the control group.
View Article and Find Full Text PDFCureus
July 2025
Cardiology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, IND.
Background Gestational diabetes mellitus (GDM) is associated with significant maternal and fetal complications, including potential effects on fetal cardiac development. This study aimed to evaluate structural and functional cardiac changes in fetuses of mothers with GDM using fetal echocardiography and to compare them with those of healthy pregnancies. The primary objective of this study was to evaluate functional cardiac changes, specifically interventricular septum (IVS) thickness and posterior wall thickness, E/A ratio (ratio of early (E) to late (A) diastolic mitral inflow velocities), and fractional shortening, in fetuses of mothers with GDM.
View Article and Find Full Text PDFEchocardiography
September 2025
Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Aims: This study sought to evaluate the feasibility, accuracy, and diagnostic performance of a fully automated deep learning model for assessing left ventricular diastolic function (LVDF) using 2D transthoracic echocardiography (TTE).
Methods And Results: In this prospective observational study, 302 patients underwent 2D TTE for suspected diastolic dysfunction. Diastolic parameters, such as mitral inflow velocities, tissue Doppler indices, left atrial volumes, and tricuspid regurgitation velocity, were automatically analyzed using AI-based software (Ligence Heart) and compared with expert manual measurements.
JACC Adv
August 2025
Department of Cardiology, National Heart Centre Singapore, Singapore; Duke-NUS Medical School, Singapore. Electronic address:
Background: Among older adults, sex hormones may exert differential effects on body fat and cardiac health.
Objectives: The authors aimed to study the effects of sex on body fat composition and aging-related diastolic function, as well as their longitudinal changes.
Methods: Community-dwelling older adults without cardiovascular disease underwent prospective baseline same-day anthropometry for body fat mass (BFM), percentage body fat (PBF), and waist hip ratio (WHR) quantification by bioimpedance and transthoracic Doppler echocardiography, with measurements repeated at 5 years.
Cureus
August 2025
Pediatric Cardiac Surgery, Bhanubhai and Madhuben Patel Cardiac Centre, Shree Krishna Hospital, Bhaikaka University, Karamsad, IND.
Inversion of the left atrial appendage (LAA) is a rare postoperative complication following cardiac surgery, often misdiagnosed as thrombus or vegetation on imaging, potentially leading to inappropriate management. We report a case of a five-month-old female infant who underwent elective surgical closure of a perimembranous ventricular septal defect via a right atrial approach under cardiopulmonary bypass. On postoperative day 2, transthoracic echocardiography (apical four-chamber view) revealed a 1 × 0.
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