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: In the context of complex aerodigestive cervical traumas, the prognosis and outcome heavily depend on risk factors, particularly injuries to the larynx, trachea, major digestive tissues, cervical vertebrae, and vascular structures. With the increasing prevalence of trauma as a public health concern, there is a pressing need for epidemiological research and the implementation of preventative measures. The purpose of this research is to establish the profile of the predictable impact factors that determine the prognosis of patients with complex cervical trauma. : The study group consisted of 106 patients with complex cervical trauma pathology developed by various mechanisms such as car accidents, home-related accidents, aggression, gunshot wounds, and self-inflicted attempts, resulting in hospitalization in the E.N.T. Clinic at "St. Spiridon" Iași Hospital, from 2012 to 2016; medical records were the source of the collected data. : Hemodynamic instability upon admission associated with age, muscle and laryngeal injuries, and anemia were identified as negative prognostic factors. Additionally, the utilization of imaging-based paraclinical investigations for diagnosing traumatic lesions emerged as a positive prognostic factor in managing this pathology. The management of penetrating cervical trauma remains a subject of debate, with some advocating for surgical exploration beyond the platysma layer in all cases, while others argue for a more selective conservative approach due to a high rate of negative explorations. : The statistical evaluation of epidemiological, clinical, lesion, paraclinical, and therapeutic parameters is needed to establish predictable risk factors in the prognosis of complex aerodigestive cervical trauma.
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http://dx.doi.org/10.3390/medicina60020238 | DOI Listing |
Sci Prog
September 2025
Department of Neurology, University of Afyonkarahisar Health Sciences, Afyonkarahisar, Türkiye.
A considerable number of individuals are diagnosed with idiopathic trigeminal neuralgia. In order to achieve a more complete understanding of the pathophysiology, it is essential to adopt a range of novel approaches and utilize new animal models. This study investigated changes in the messenger RNA (mRNA) expression of ion-channels in a newly developed animal model of trigeminal neuropathic pain induced by cervical spinal dorsal horn compression.
View Article and Find Full Text PDFLasers Med Sci
September 2025
Department of Otolaryngology Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, 71 Hexi Street, Nanjing 210019, Jiangsu, China.
To evaluated the efficacy of photodynamic therapy (PDT) in improving laryngeal mucosal wound scar healing in vivo and investigated its underlying mechanisms. Laryngeal mucosal wounds were induced in Sprague-Dawley rats. Two weeks post-injury, PDT was administered via intraperitoneal injection of 100 mg/kg 5-aminolevulinic acid (5-ALA) and 635-nm red laser irradiation at varying energy doses (15, 30, and 45 J/cm²).
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
September 2025
Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai, China.
Purpose: To investigate the images and treatment differences for Type IIIa atlantoaxial rotary dislocation (AARD) by comparing the imaging characteristics of patients with Type III and Type IIIa AARD.
Methods: The present study retrospectively analyzed a cohort of 35 patients who underwent posterior C1-C2 intra-articular fusion due to AARD from our hospital database. Among them, 23 patients were diagnosed with Type III AARD, while the remaining 12 patients were diagnosed with Type IIIa AARD.
Eur Arch Psychiatry Clin Neurosci
September 2025
School of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Concerns over the mental health among young people have been increasing recently. We aimed to estimate the burdens of mental disorders, substance use disorders (SUDs), and self-harm at global, regional and national levels among adolescents and young adults aged 10-24 years from 1990 to 2021. Incidence, prevalence, and disability-adjusted life years (DALYs) of mental disorders, SUDs, and self-harm among young people were examined by age, sex, region, and country/territory.
View Article and Find Full Text PDFInt Arch Occup Environ Health
September 2025
Department of Mechanical Engineering, Politecnico di Milano, Milan, Italy.
Purpose: To investigate the role of personal risk factors in the occurrence of the vascular, neurological and fibroproliferative disorders of the hand-arm vibration syndrome (HAVS) in workers groups exposed to hand-transmitted vibration (HTV).
Methods: HAVS prevalence and incidence data were pooled across a series of cross-sectional studies (total sample: 1272 HTV workers, 579 controls) and prospective cohort studies (total sample: 377 HTV workers, 138 controls) conducted in Central and North-Eastern Italy. The pooled studies included detailed individual-level information about HTV exposure, personal risk factors, medical comorbidities and HAVS disorders.