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Objectives: This article describes Pathologists Overseas (PO) experience supporting external quality assessment (EQA) programs in 10 clinical laboratories across 3 countries between 2009 and 2017.
Methods: Laboratories were enrolled in the condensed chemical pathology EQA program provided by the Royal College of Pathologists of Australasia Quality Assurance Program. Participants were given an initial 2- to 4-day in-person training, followed by 1 year of active feedback on performance via emails or phone calls by a PO volunteer.
Results: There were 2 performance metrics: percentage of reported results as a measure of compliance and percentage of acceptable reported results as a measure of accuracy. Laboratories demonstrated high compliance with result reporting, with medians of 69.9%, 71.7%, and 81.3% before, during, and after feedback, respectively. Concomitant medians for the percentage of acceptable reported results were 41.2%, 57.3%, and 53.5%, respectively. Six laboratories had low performance in terms of accuracy at baseline (<60%). Active feedback improved the percentage of acceptable reported results for these lower-performing laboratories.
Conclusions: External quality assessment programs can be successfully adopted long term by laboratories in low-resource settings. Active feedback requires significant time and effort but could be especially beneficial for laboratories with poor baseline performance.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11519028 | PMC |
http://dx.doi.org/10.1093/ajcp/aqae009 | DOI Listing |
Menopause
September 2025
Bayer Consumer Care, Basel, Switzerland.
Importance: Sleep disturbances are common during and after the menopause transition, with potential effects on morbidity and quality of life; however, they may be underdiagnosed and undertreated.
Objective: We carried out a systematic literature review to investigate the prevalence and impact of sleep disturbances associated with menopause on women's health-related quality of life across the stages of menopause.
Evidence Review: Searches were conducted in PubMed and Excerpta Medica Database to identify articles published between 2013 and 2023 containing evidence for the impact of sleep quality on health-related quality of life and the epidemiology of sleep disturbances in women in menopause.
Anal Methods
September 2025
Jilin Province Product Quality Supervision and Inspection Institute, Changchun 130103, China.
A method for determination of ten kinds of sweeteners in soybean products by multi-plug filtration cleanup (-PFC) combined with ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was established. The sample was extracted with acetonitrile (containing 1% formic acid), degreased by using -hexane liquid-liquid extraction and purified by solid phase extraction using an -PFC column (Oasis PRiME HLB). The analytes were separated by using a Waters ACQUITY UPLC® BEH C (2.
View Article and Find Full Text PDFEur J Clin Pharmacol
September 2025
Department of Hospital Pharmacy, Meander Medical Centre, Amersfoort, the Netherlands.
Purpose: This study was designed to analyse the influence of temperature, pH and storage time on unbound fractions of PHT and VPA.
Methods: The influence of ultrafiltration (UF) temperature on measured unbound fractions of PHT and VPA in spiked samples was evaluated in a single laboratory experiment and in data from a national external quality control (EQC) database. The influence of pH adjustment with phosphate buffered saline (PBS) on measured unbound fractions of PHT and VPA was investigated in patient samples.
Medicine (Baltimore)
September 2025
Nursing Department, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Stroke is a severe neurological disorder that significantly impacts patients' recovery and quality of life. Stroke patients frequently experience sleep disorders, including difficulty initiating sleep, insomnia, vivid dreams, and sleep apnea. These disorders not only disrupt nighttime rest but also significantly affect stroke recovery and prognosis, increasing the risks of recurrence and mortality.
View Article and Find Full Text PDFIndian J Gastroenterol
September 2025
Department of GI Surgery, HPB and Liver Transplantation, Post Graduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
Introduction: Bile duct injury (BDI) is a potentially devastating complication of cholecystectomy. Although the repair may be successful, patients often experience a decline in their quality of life (QoL). However, there is a paucity of data regarding the factors influencing long-term outcomes and QOL in these patients.
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