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Introduction: In 2015, the term 'intrinsic capacity' (IC) was proposed by the World Health Organisation to promote healthy aging. However, the factors associated with IC are still discrepant and uncertain.
Aim: We aim to synthesise the factors connected with IC.
Methods: This scoping review followed the five-stage framework of Arksey and O'Malley and was reported using PRISMA-ScR guidelines.
Results: In all, 29 articles were included. IC of older adults is associated with demographic characteristics, socioeconomic factors, disease conditions, behavioural factors, and biomarkers. Age, sex, marital status, occupation status, education, income/wealth, chronic diseases, hypertension, diabetes, disability, smoking status, alcohol consumption, and physical activity were emerged as important factors related to the IC of older adults.
Conclusions: This review shows that IC is related to multiple factors. Understanding these factors can provide the healthcare personnel with the theoretical basis for intervening and managing IC in older adults.
Relevance To Clinical Practice: The influencing factors identified in the review help to guide older adults to maintain their own intrinsic capacity, thereby promoting their health and well-being. The modifiable factors also provide evidence for healthcare personnel to develop targeted intervention strategies to delay IC decline.
No Patient Or Public Contribution: As this is a scoping review, no patient or public contributions are required.
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http://dx.doi.org/10.1111/jocn.17017 | DOI Listing |
J Magn Reson Imaging
September 2025
Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.
Background: Cerebrovascular reactivity reflects changes in cerebral blood flow in response to an acute stimulus and is reflective of the brain's ability to match blood flow to demand. Functional MRI with a breath-hold task can be used to elicit this vasoactive response, but data validity hinges on subject compliance. Determining breath-hold compliance often requires external monitoring equipment.
View Article and Find Full Text PDFHum Brain Mapp
September 2025
Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Perinatal stroke is a vascular injury occurring early in life, often resulting in motor deficits (hemiplegic cerebral palsy/HCP). Comorbidities may also include poor neuropsychological outcomes, such as deficits in memory. Previous studies have used resting state functional MRI (fMRI) to demonstrate that functional connectivity (FC) within hippocampal circuits is associated with memory function in typically developing controls (TDC) and in adults after stroke, but this is unexplored in perinatal stroke.
View Article and Find Full Text PDFNeuropsychol Dev Cogn B Aging Neuropsychol Cogn
September 2025
Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Cognitive function is a critical health indicator of older adults in later life. However, previous research has paid less attention to the impact of pre-retirement work-related characteristics on cognitive functions, especially in Asia. Thus, this study aims to examine the relationship between work-related factors and cognitive functions of the retired population, using Taiwan as an example.
View Article and Find Full Text PDFAnn Geriatr Med Res
September 2025
Institute of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan.
Background: Poor hand dexterity may increase the risk of functional disability; however, few studies have examined the relationship between hand dexterity and incident functional disability. The aim of this study was to prospectively investigate the dose-response association of hand dexterity with incident functional disability in community-dwelling older adults.
Methods: This study included 1,069 older adults aged ≥65 years in Kasama City, Japan.
Foot Ankle Int
September 2025
Department of Radiology, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan.
Background: Coronal wedge insoles are commonly prescribed to mitigate musculoskeletal disorders, yet their static-standing kinematic and kinetic effects on lower extremity joints remain insufficiently understood.
Methods: This cross-sectional experimental study included 15 healthy older adults (mean 64.9 ± 6.