98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11146545 | PMC |
http://dx.doi.org/10.1164/rccm.202401-0090ED | DOI Listing |
Environ Res
September 2025
Department of Occupational and Environmental Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Denmark; Department of Public Health, Section of Environmental Health, University of Copenhagen, Denmark.
Background: Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) may influence lung and immune system development, but previous epidemiological studies are inconclusive and have not extended into young adulthood.
Objective: To examine associations between prenatal exposure to a mixture of PFAS and respiratory and immune-related outcomes in a cohort of males.
Methods: We studied 866 males with maternal pregnancy plasma measured for 15 PFAS, triclosan, and nine phthalate metabolites used as a proxy for prenatal exposure.
Eur Respir Rev
July 2025
Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China
Background: Limited evidence exists on air pollution's systemic impact on lung function and mediating biomarkers. This study comprehensively evaluated associations between air pollution, COPD and lung function, while exploring biomarker mediation.
Methods: A prospective analysis of 451 566 UK Biobank participants was conducted.
Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive lung function decline, commonly measured by forced expiratory volume in one second (FEV). Uncovering the genetic basis of FEV decline is essential for understanding COPD pathophysiology and for developing therapies. We hypothesized that gene expression patterns in inflammatory pathways are associated with FEV decline.
View Article and Find Full Text PDFBalkan Med J
September 2025
Department of Radiology, Gazi University Faculty of Medicine, Ankara, Türkiye
Background: Childhood bronchiectasis (BE) is a chronic lung condition that remains under recognized, marked by irreversible widening of the bronchi, frequent respiratory infections, a persistent wet cough, and progressive lung damage, often leading to significant health burdens.
Aims: To evaluate children with cystic fibrosis (CF) and non-CF BE and to examine the association between clinical presentation and radiological severity of BE using the Bhalla scoring system.
Study Design: Retrospective observational study.
J Allergy Clin Immunol
August 2025
The University of Wisconsin School of Medicine and Public Health, Madison.
Background: The American Thoracic Society recently recommended that race- and ethnicity-specific predicted equations for spirometry be replaced with race-neutral equations. This change could have implications for asthma management.
Objective: Our aim was to examine the effect of race-specific versus race-neutral spirometry reference equations on the resultant guideline-directed asthma therapy in a study population with a high proportion of Black children.