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•SABR has shown survival benefits in oligometastatic cases, particularly in low-volume metastatic disease states.•Spine SABR offers potential improvements in local control, and pain response for metastatic spine tumors.•Technical requirements for SABR, like advanced image guidance and immobilization systems, are increasingly available.•Current data suggests high local control rates (75-95%) and variable pain responses (40-90%) with SABR using single or multi-fraction regimens.•Further randomized trials are needed to explore SABR applications in different scenarios and populations, while considering global health aspects for wider accessibility.
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http://dx.doi.org/10.1016/j.ctro.2024.100728 | DOI Listing |
Pediatr Blood Cancer
September 2025
Nuffield Department of Surgical Sciences, Oxford University, Oxford, UK.
Background: Local control strategies in pediatric oncology are guided by disease-specific considerations. Effective communication of the goals of surgical procedure and associated intraoperative events plays a crucial role in shaping subsequent treatment decisions. However, accurately and comprehensively documenting these findings remains challenging, with considerable variability across different tumor types.
View Article and Find Full Text PDFAlzheimers Res Ther
September 2025
Motor Control and Learning Group, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Leopold-Ruzicka-Weg 4, Zurich, 8093, Switzerland.
Eur J Oral Sci
September 2025
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People's Re
Oral lichen planus (OLP) is a chronic inflammatory disease of unknown aetiology, which is an oral potentially malignant disorder. Many investigators suggest that OLP may be a localized autoimmune response caused by cell-mediated autoimmunity to basal cells. However, it remains unclear whether allergens play a role in the pathogenesis of OLP.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
School of Life Sciences, Chongqing University, Chongqing 401331, China; Chongqing Engineering Research Center for Fungal Insecticides, Chongqing 401331, China; Key Laboratory of Gene Function and Regulation Technologies under Chongqing Municipal Education Commission, Chongqing 401331, China; Nationa
Entomopathogenic fungi such as Metarhizium acridum are pivotal for sustainable pest management, yet the industrial conidial production is hindered by low yields and environmental sensitivity. Transcriptional regulation provides key targets for engineering strain modification. AP-1 transcription factors (TFs) are well-known for their roles in fungal growth, development, conidiation, pathogenicity and stress tolerance across various fungi.
View Article and Find Full Text PDFFungal Biol
October 2025
School of Life and Health Sciences, Hainan University, Haikou, Hainan, 570228, China; Hainan Province Key Laboratory of One Health, Hainan University, Haikou, Hainan, 570228, China. Electronic address:
Maize anthracnose, caused by the fungal pathogen Colletotrichum graminicola, is among the most devastating diseases affecting maize production. Homeobox transcription factors (HTFs) regulate key developmental and physiological processes in eukaryotes, including fungal pathogenesis. In this study, we identified two HTFs, CgrHtf1 and CgrAfh1, in C.
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