Cytoskeleton crosstalk: Casting stable actin bundles with dynamic microtubule molds.

Curr Biol

Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

Published: January 2024


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Article Abstract

Actin-microtubule crosstalk diversifies cytoskeletal networks. A new study provides insight into how the microtubule polymerase CKAP5 mediates actin-microtubule crosstalk. CKAP5 directs the assembly of stable actin bundles on dynamic microtubules; in turn, the actin bundles align growing microtubules along their length.

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http://dx.doi.org/10.1016/j.cub.2023.12.028DOI Listing

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