Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

A paper-based ratiometric fluorescent sensing platform has been developed for glucose detection based on a dual-emission fluorescent probe consisting of carbon quantum dots (C QDs) and CdTe QDs. When the two kinds of QDs are mixed, the fluorescence of C QDs is reversibly quenched by CdTe QDs. However, in the presence of glucose, the fluorescence of CdTe QDs is quenched by HO catalyzed by glucose oxidase (GOx), which restores the fluorescence of C QDs. The proposed paper-based ratiometric fluorescent sensing platform exhibited good sensitivity and selectivity towards glucose. The working linear range was 0.1 mM to 50 mM with a limit of detection (LOD) of 0.026 mM. Additionally, the proposed paper-based sensor possesses viability for the determination of glucose in actual urine samples.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10762332PMC
http://dx.doi.org/10.1039/d3ra07082dDOI Listing

Publication Analysis

Top Keywords

paper-based ratiometric
12
ratiometric fluorescent
12
fluorescent sensing
12
sensing platform
12
cdte qds
12
quantum dots
8
fluorescence qds
8
proposed paper-based
8
qds
7
glucose
6

Similar Publications

The pervasive concern regarding veterinary drug residues in food necessitates advanced detection solutions, particularly addressing limitations of conventional methods reliant on large-scale instrumentation that incur prolonged analysis duration, complex sample preparation, and lack of real-time on-site capability. A portable "single response-on" molecularly imprinted ratiometric fluorescent paper-based sensor was developed for quantifying fleroxacin (FLX) residues in animal-derived foods, wherein B, N-co-doped MXene quantum dot (B, N-MQD) was synthesized and combined with BCP-Eu as dual-emission fluorophores, while FLX- molecularly imprinted polymer (FLX-MIP) was engineered using functionalized Nano-SiO as the carrier. Concentration-dependent fluorescence enhancement at 574 nm was exhibited with invariant reference signal at 411 nm, achieving a 36-fold lower detection limit (0.

View Article and Find Full Text PDF

Portable Ratiometric Fluorescence Sensor for Immediate Creatinine Detection in Early Medical Screening.

Adv Healthc Mater

September 2025

Hubei Engineering Technology Research Center of Spectrum and Imaging Instrument, Electronic Information School, Wuhan University, Wuhan, 430072, China.

Accurate and rapid detection of urinary creatinine (CR) is critical for early kidney disease screening and efficient healthcare resource management. In this study, a novel colorimetric-fluorescent sensor is developed by integrating nitrogen-doped carbon dots (N-CDs) and copper nanoclusters (CuNCs) with gold nanoparticles (AuNPs), leveraging fluorescence resonance energy transfer (FRET) to enhance sensitivity and selectivity. The sensor functions within a detection range of 1-50 mm, with peak responsiveness at 17 mm, utilizing paper-based substrates for a low-cost and portable application.

View Article and Find Full Text PDF

, a versatile human pathogen, significantly impacts global health causing a broad spectrum of medical conditions that range from minor skin infections to life-threatening diseases. The clinical importance of is underscored by its resistance to multiple antibiotics and formation of biofilms, providing protection against antimicrobials and immune responses. To date, the identification of antimicrobial-resistant (AMR) strains, such as methicillin-resistant (MRSA) and vancomycin-intermediate (VISA), requires time-consuming and expensive methodologies, including culture-based, molecular, and phenotypic techniques.

View Article and Find Full Text PDF

A smartphone-assisted fluorescent and colorimetric detection method for nitrite based on 2,3-diaminonaphthalene (DAN) and gold nanoclusters (AuNCs) paper strip was developed. DAN reacts with NO via a coupling reaction under acidic conditions to generate naphthotriazole (NAT), emitting strong blue fluorescence at 435 nm. The red fluorescence of AuNCs at 650 nm is quenched by the reduction of nitrite.

View Article and Find Full Text PDF

This review explores the evolution and application of fluorescence sensors based on quantum dots (QDs) for detecting environmental and biological analytes across diverse real-world scenarios and complex sample matrices and also categorizes different types of quantum dots, such as carbon dots (C-dots), graphene quantum dots (GQDs), and metal-doped QDs and examines their properties, including tunable fluorescence, low toxicity, and photostability, which make them ideal for a variety of applications. Key sensing mechanisms, including Förster Resonance Energy Transfer (FRET) and fluorescence quenching, are discussed alongside innovations like paper-based, ratiometric, and turn-on/turn-off sensors. Additionally, case studies are provided to showcase the application of these sensors in environmental and biomedical fields, where they provide rapid, sensitive, and cost-effective solutions.

View Article and Find Full Text PDF