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Unlabelled: The aim of the study was to investigate how obesity can influence sleep respiratory parameters in obstructive sleep apnea syndrome (OSAS) in children.
Methods: The study analyzes 56 Caucasian children and adolescents aged 11 ± 2.79 years with a BMI > 5th percentiles and a PSQ value ≥ 0.33. Children were divided into Obesity Group (OG) with BMI ≥ 95th and Control Group (CG) with 5th < BMI > 95th percentile. All selected children underwent PG. Respiratory parameters AHI (Apnea-Hypopnea Index), SaO (Saturation of Oxygen), ODI (Oxygen Desaturation Index), and Nadir (the lowest value of SaO registered during PG) were extracted from the PG. AHI was used to divide the severity of OSAS into four levels: snoring (AHI ≤ 1), mild (AHI > 1 and ≤5), moderate (AHI > 5 and <10), and severe (AHI ≥ 10).
Results: The comparison analysis between the OG and CG showed a statistical significance only for ODI ( = 0.02). A statistically significant correlation between BMI and AHI (r = 0.02), SaO (r = 0.01), and Nadir O (r = 0.02) was found.
Conclusions: There was no strong correlation between obesity and OSAS, but a positive association was found between BMI and AHI severity.
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http://dx.doi.org/10.3390/children10121874 | DOI Listing |
Comput Methods Programs Biomed
September 2025
School of Biological Sciences and Medical Engineering, Southeast University, Nanjing, Jiangsu, China. Electronic address:
Background And Objective: The quantitative knowledge of the influence of the small airway disease on the functional changes in chronic obstructive pulmonary disease (COPD) patients has been severely limited.
Methods: This study presents an innovative patient-specific computational framework that integrates CT and OCT imaging data with multiscale computational fluid dynamics (CFD) analysis. A three-dimensional tracheobronchial tree is reconstructed from CT scans of a mild COPD patient, spanning from the central airway to the 4th generation bronchial bifurcations.
J Plant Physiol
September 2025
Department of Plant Physiology, University of Granada, Granada, Spain. Electronic address:
Legumes form symbioses with nitrogen-fixing bacteria, well studied metabolically but less so in terms of respiration. Symbiotic nitrogen fixation demands high respiratory ATP and carbon skeletons, linking nitrogen assimilation and both NADH- and ATP-dependent process to mitochondrial respiration. The plant mitochondrial electron transport chain contains two terminal oxidases that differentially fractionate against O, providing estimations in vivo of the energy efficiency of respiration.
View Article and Find Full Text PDFEquine Vet J
September 2025
Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
The need for comprehensive equine welfare assessments has become particularly evident amid ongoing debates about the social licence to operate in equestrian sports. During exercise, multiple physiological systems, principally the cardiovascular, respiratory, muscular, thermoregulatory, endocrine, and locomotory systems, undergo complex adaptations. To monitor and determine equine welfare, an approach that focuses on the quantitative monitoring of both physiological and psychological parameters to determine and understand the impact of equestrian sports on horses is essential.
View Article and Find Full Text PDFEur J Pediatr
September 2025
Division of Pulmonology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.
Unlabelled: Obesity is a pervasive global health issue frequently associated with metabolic syndrome (MetS). Limited data exist regarding the impact of MetS and its individual components on pulmonary function in obese pediatric populations. This study investigated the relationship between MetS and lung function, and further identified specific MetS components that adversely affect pulmonary outcomes.
View Article and Find Full Text PDFProg Nucl Magn Reson Spectrosc
September 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom; School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile; Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile; Institute for Biological and Medical
Cardiovascular magnetic resonance (CMR) imaging is an established non-invasive tool for the assessment of cardiovascular diseases, which are the leading cause of death globally. CMR provides dynamic and static multi-contrast and multi-parametric images, including cine for functional evaluation, contrast-enhanced imaging and parametric mapping for tissue characterization, and MR angiography for the assessment of the aortic, coronary and pulmonary circulation. However, clinical CMR imaging sequences still have some limitations such as the requirement for multiple breath-holds, incomplete spatial coverage, complex planning and acquisition, low scan efficiency and long scan times.
View Article and Find Full Text PDF