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Key Clinical Message: Spinal cord herniation is an uncommon diagnosis. There should be a high index of suspicion to diagnose spinal cord herniation when a patient presents with incomplete neurological deficits. Surgical repair of the hernia can have postoperative complications with new neurological deficits and they should be considered during the treatment.
Abstract: A 37-year-old male presented with insidious onset upper back pain and altered sensations of pain and temperature over the right half of the body below the nipple for 2 months. MRI of the thoracic spine showed an anterolateral defect (left) at the level of T2-T3 vertebra. The defect was covered by a dural graft and the wound was closed with a drain On the 3rd postoperative day, neurological weakness progressed to paraplegia. Patient was treated by exploration and decompression of the hematoma. The deficits were completely recovered at one-month follow-up. Patients with spinal cord herniation and neurologic deficits when treated timely have good outcomes.
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http://dx.doi.org/10.1002/ccr3.8246 | DOI Listing |
Neurol Res
September 2025
Toxicology Research Center, AJA University of Medical Sciences, Tehran, Iran.
Background: Free radicals play a key role in spinal cord injury and curcumin has the potential to act as an antioxidant agent. Controlled delivery of curcumin can be achieved through encapsulation in bovine serum albumin to form nanoparticles, and acellular scaffold can bridge lesions and improve axonal growth in spinal cord injury.
Objective: In this study, we evaluated the antioxidant effects of the scaffold containing curcumin nanoparticles in the unilateral spinal cord injury model in male rats.
Br J Nurs
September 2025
Senior Bladder, Bowel and Stoma Care, Clinical Nurse Specialist and Nurse Prescriber, Hollister Ltd.
The aim of this case study is to illustrate the benefits of clean intermittent self-catheterisation (CISC) in individuals with multiple sclerosis (MS) who have incomplete bladder emptying. People with MS usually start to experience bladder symptoms 6-8 years after diagnosis, although some individuals experience symptoms from the time of diagnosis. MS is a condition of the central nervous system that affects the brain and spinal cord; the immune system attacks myelin, a substance that protects the nerve fibres, preventing messages travelling smoothly along the fibres to control the whole body, which includes the nerves that control the bladder.
View Article and Find Full Text PDFCNS Neurosci Ther
September 2025
School of Information and Communication Engineering, North University of China, Taiyuan, China.
Aims: Decoding the motor intention by electroencephalography to control external devices is an effective method of helping spinal cord injury (SCI) patients to regain motor function. Still, SCI patients have much lower accuracy in the decoding of motor intentions compared to healthy individuals, which severely hampers the clinical application. However, the underlying neural mechanisms are still unknown.
View Article and Find Full Text PDFJ Neuroimaging
September 2025
Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Background And Purpose: Socioeconomic determinants of health impact childhood development and adult health outcomes. One key aspect is the physical environment and neighborhood where children live and grow. Emerging evidence suggests that neighborhood deprivation, often measured by the Area Deprivation Index (ADI), may influence neurodevelopment, but longitudinal and multimodal neuroimaging analyses remain limited.
View Article and Find Full Text PDFCurr Microbiol
September 2025
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
This review article describes recent research advances in the relationship between spinal cord injury (SCI) and the gut microbiota and each other's inflammatory response. SCI is a serious neurological disease that directly damages physiological function. Recent studies have shown that SCI significantly affected the composition and function of the gut microbiota, and even caused intestinal inflammation.
View Article and Find Full Text PDF