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Background: The prevalence of cannabis use disorder and its negative consequences among young adults has highlighted the need for prevention and early intervention programs. However, low treatment prevalence persists due to factors such as lack of perceived need, concerns about stigma, and limited access to treatment. To address these barriers, web-based cannabis interventions have been developed, but their efficacy remain limited. This study aims to evaluate the cross-site efficacy of the Cannabis eCHECKUP TO GO program, a web-based Personalized Normative Feedback and Protective Behavioral Strategies intervention for reducing cannabis use frequency and consequences in college students with willingness to change.
Methods: Participants were 781 students from three universities (two in Canada, one in the US) who reported using cannabis in the past month and expressed interest in reducing or engaging in safer cannabis use. The study randomly assigned them to either an experimental group that received personalized normative feedback or a control group that received information on healthy stress management. The study collected follow-up data 4 weeks after the initial intervention and measured participants' frequency of cannabis use, number of cannabis consequences, descriptive and injunctive norms at both time points.
Results: The results showed no significant reductions in cannabis use or negative consequences of use. However, students who received personalized normative feedback experienced a significant reduction in descriptive norms related to cannabis use, to be more in line with actual use.
Conclusion: This study suggests that more targeted interventions may be necessary for university students who are already using and seeking help to reduce their use.
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http://dx.doi.org/10.1016/j.josat.2023.209267 | DOI Listing |
JAMA Netw Open
September 2025
School of Medicine and Public Health, University of Wisconsin-Madison, Madison.
Importance: It is unclear whether the duration of amyloid-β (Aβ) pathology is associated with neurodegeneration and whether this depends on the presence of tau.
Objective: To examine the association of longitudinal atrophy with Aβ positron emission tomography (PET)-positivity (Aβ+) and the estimated duration of Aβ+ (Aβ+ duration), controlling for tau-positivity.
Design, Setting, And Participants: Data for this longitudinal cohort study were drawn from the Wisconsin Registry for Alzheimer Prevention and the Wisconsin Alzheimer Disease Research Center Clinical Core Study.
S Afr J Commun Disord
August 2025
Department of Speech Pathology and Audiology, Faculty of Humanities, University of the Witwatersrand, Johannesburg, South Africa; and Department of Rehabilitative and Natural Sciences, Faculty of Health Sciences, University of Fort Hare, East London.
Background: The people of the Pedi culture place great value on, and take pride in, adhering to their culture, as reflected in the manner in which they communicate verbally and non-verbally. However, little is documented about the ways in which verbal and non-verbal language is used socially by the younger generations in the Pedi culture.
Objectives: This article examines how verbal and non-verbal social language skills and functions are used by the younger generations in Pedi families.
Food Res Int
November 2025
Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, Japan. Electronic address:
High-risk eating behavior, including the consumption of rare hamburgers and undercooked chicken as gourmet dishes, is a public health concern. Identifying the factors associated with such consumers' risky-eating behaviors is necessary to develop effective risk communication strategies. However, previous studies have primarily focused on undercooked meat resulting from mishandling during preparation, with few addressing the consumption of risky foods and its determinants.
View Article and Find Full Text PDFSci Data
September 2025
Department of Neurosurgery, University Hospital Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany.
Angiographic normative values for the size of intracranial vessels are difficult to obtain, since they vary with gender, height and weight. Cerebral angiography only is indicated in severe cerebrovascular diseases, which also can affect cerebral vessel diameters, impeding the definition of physiological values. To approximate "normal" values, over 1000 contemporary cerebral angiographies from a single neurovascular centre were analyzed.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA. Electronic address:
Purpose: To compare retinal ganglion cell (RGC) loss in glaucoma suspect eyes with diffuse versus localized neuroretinal rim loss at the time of the first confirmed visual field defect.
Design: Prospective observational cohort study.
Subjects: Fifty-three glaucoma suspect eyes and 124 healthy eyes.