Publications by authors named "Mark A Prince"

Objective: Cannabis retail dispensaries have proliferated in the United States in recent years, making it an important time for conducting research. Research is needed to learn more about consumer purchasing behaviors, including the impact of product marketing both inside and outside of retail spaces, and studies are needed to explore how both consumers and retail staff interpret the health benefits and potential risks associated with cannabis products within these environments. Current research on cannabis dispensaries often involves surveys or interviews with customers and dispensary staff outside of dispensary environments, but much can be learned through observational and experimental methods within dispensaries themselves.

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Objective: Cannabis use can result in negative cannabis-related consequences (NCRC), particularly among individuals high in impulsivity and sensation seeking. Continued research is necessary to determine if these associations generalize to community adults with daily legal cannabis use. We hypothesized that impulsivity and sensation seeking would positively predict NCRC.

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Background: Though the link between alcohol use and alcohol-related problems is intuitive, meta-analyses show that drinking explains <20% of the variance in problems. This suggests that other factors play an important role in when and for whom drinking leads to problems. Moreover, most research in this area has relied on either cross-sectional data or macrolongitudinal methods (e.

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Short-term memory (STM) challenges are often observed in children with Down syndrome (DS), but existing early STM measures introduce measurement confounds in this population. To address the need for valid early STM measures for future DS interventions, this study evaluated the psychometric properties of a modified Corsi Span task, administered to 110 children with DS. Results indicated that the modified Corsi task has feasibility in the age range of 5-8 years and is scalable across chronological and mental ages.

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Executive function (EF) is frequently an area of vulnerability in conditions associated with intellectual disability, like Down syndrome (DS). However, current EF evaluation approaches are not designed for children with underlying neurodevelopmental conditions and may not demonstrate construct validity due to interpretational confounds. The current study evaluated the construct validity of a novel battery designed to reduce measurement confounds in the assessment of EF in young children with DS.

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Background: Individuals with Down syndrome (DS) have an elevated likelihood of challenges with executive function (EF) throughout the lifespan, and syndrome-informed intervention approaches that strengthen these foundations during early childhood may be beneficial. This single group baseline versus postintervention pilot study presents findings from the implementation of a syndrome-informed, parent-mediated intervention designed to support the development of EF in preschool-aged children with DS (EXPO: Executive Function Play Opportunities).

Method: Participants were 34 children aged 3-7 years old with DS and their caregivers.

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Purpose: Social support is an important factor in shaping healthcare navigation, coping, and psychological outcomes among pediatric cancer caregivers. Socioeconomic status is positively associated with satisfaction with social support, however, less is understood about network features that contribute to these differences. Social networks are the context in which resources and support are exchanged.

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Importance: Preclinical, observational, and pharmacoepidemiology evidence indicates that glucagon-like peptide 1 receptor agonists (GLP-1RAs) may reduce alcohol intake. Randomized trials are needed to determine the clinical significance of these findings.

Objective: To evaluate the effects of once-weekly subcutaneous semaglutide on alcohol consumption and craving in adults with alcohol use disorder (AUD).

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Background: Simultaneous alcohol and marijuana use (SAM) and food restriction on days students intend to drink are associated with an increased risk of substance use-related consequences. However, these negative outcomes have been studied mostly in alcohol-only use contexts. Little is known about the combination of alcohol, marijuana, SAM, and food restriction.

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Article Synopsis
  • The study aimed to see if a mindfulness-based intervention (MBI) helps adolescents cope better with chronic stress compared to just mentoring alone.
  • Researchers worked with 81 adolescents, collecting data on their mindfulness and emotion regulation through daily assessments before, during, and after the intervention.
  • Results showed that MBI combined with mentoring slightly improved how adolescents managed stress, suggesting that mindfulness training could help buffer against the negative effects of stress in their daily lives.
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Proper diagnosis is essential in mitigating risk associated with sports-related concussion (SRC); however, 50% of SRCs remain undiagnosed due to unreported symptoms. The current study aimed to identify the clinically-relevant, attainable personality and social determinants of health variables that are associated with honesty and comfortability reporting symptoms in 317 adolescents ( = 17.8, SD = 0.

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Background: American Indian (AI) adolescents report earlier initiation and higher rates of cannabis and alcohol use compared to their non-AI peers. Simultaneous cannabis and alcohol (SCA) use is increasingly common. A primary goal of our research was to identify profiles of cannabis and alcohol use, including SCA use, among AI adolescents using latent class analysis (LCA).

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Background: Reservation-area American Indian (AI) youth use cannabis at significantly higher rates than their national counterparts. This discrepancy is concerning, as cannabis use-particularly heavy use-can negatively impact adolescents' health. Studies primarily use frequency to classify cannabis use intensity; however, frequency alone may not fully capture heterogenous patterns of use.

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There is a high need for accessible avenues for improving mental health among emerging adults, particularly on college campuses. Mindfulness-based intervention (MBI) is a promising avenue for reducing mental health symptoms, but initial discomforts associated with MBI may cause symptoms to fluctuate before decreasing, which presents a barrier to engagement with mindfulness on a daily basis. Consistent mindfulness practice is key for forming habits related to MBI, and engagement with mindfulness at home, including between intervention sessions, is an important predictor of mental health outcomes.

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Adolescents faced with chronic stressors (e.g., financial instability, interpersonal violence) are at heightened risk for developing mental health problems, likely due in part to stressors that interfere with effective emotion regulation.

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Purpose: This study aims to examine a second-order latent variable of family functioning built from two established protective factors for American Indian (AI) youth, i.e. family cohesion and parental monitoring.

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Background: While research has examined the effect of stigma from others towards individuals with substance use disorders, few studies have examined the relationship between perceived self-stigma and engagement in substance use more broadly, especially among non-clinical samples.

Aims: The present study examined the relationships between perceptions of self-stigma if one were to develop a substance use disorder, consisting of negative self-esteem and negative self-efficacy, and alcohol or marijuana use behaviors and outcomes.

Method: Participants (n = 2,243; 71.

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Operant conditioning and social learning theories suggest that positive cannabis use-related outcomes are a primary contributor to maintained use and risk for dependence. However, currently there does not exist a reliable, validated measure of positive cannabis-related outcomes. This study sought to develop and psychometrically evaluate the Positive Outcomes of Cannabis Use Scale (POCUS).

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Objective: Pregaming is common among college students and is associated with heavy drinking and negative alcohol-related consequences. The use of cannabis on pregaming days may exacerbate negative alcohol-related consequences, and the ordering of when cannabis is used on these days may buffer against or intensify these consequences. Considering the growing rates of simultaneous use of cannabis and alcohol among college students, it is necessary to examine the role of pregaming behaviors in the context of cannabis use and its effects on alcohol-related consequences.

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Background: Alcohol misuse among college students is a public health concern. Protective behavioral strategies (PBS) can be used before, during, after, or instead of drinking to reduce alcohol use and negative consequences, but findings on their utility at the aggregate level are mixed. Although recent work has provided important information on the performance of individual PBS items, it is limited by research designs that are cross-sectional, do not examine consequences, or do not examine other important correlates, such as drinking motives.

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Background: The prevalence of cannabis use disorder and its negative consequences among young adults has highlighted the need for prevention and early intervention programs. However, low treatment prevalence persists due to factors such as lack of perceived need, concerns about stigma, and limited access to treatment. To address these barriers, web-based cannabis interventions have been developed, but their efficacy remain limited.

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