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In this study, numerical simulation was employed to predict the performance and internal flow characteristics of the inlet of an axial-flow pump by assigning an absolute flow angle to the inlet guide vane (IGV) trailing-edge flow. Further, the finite volume method based on the three-dimensional Reynolds-averaged Navier-Stokes equations was employed to discretize the governing equations. The shear stress transport model was used as the turbulence model, and an appropriate number of nodes were selected for the hexahedral grid system through a grid-dependency test. The performance curve and changes in the internal flow field were investigated based on the variation in the flow angle at the inlet of the axial-flow pump. These results can be used to establish an efficient operational plan by adjusting the IGV angle of IGV when installing a variable IGV for an axial-flow pump.
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http://dx.doi.org/10.1038/s41598-023-49671-4 | DOI Listing |
Front Bioeng Biotechnol
August 2025
Anzhen Hospital, Capital Medical University, Beijing, China.
Objective: Fontan surgery constructs Total Cavo-Pulmonary Connection Circulation (TCPC), but lacks power. Cavopulmonary circulation assist devices (CPAD) has been proposed to support the Fontan circulation. The virtual implantation of blood pumps into the real TCPC structure to analyze the output characteristics of blood pump and flow pattern can better guide design of the pump and the formulation of powered Fontan surgical protocols.
View Article and Find Full Text PDFInt J Artif Organs
July 2025
Enna and Centro Cuore GB Morgagni, Kore University, Catania, Italy.
Platelet derived prothrombotic microparticles (MP) have been associated with hemocompatibility related adverse events in patients with continuous flow left ventricular assist devices; little is known with the contemporary Impella platform micro-axial flow pumps. Indeed, the extended duration of support provided by the Impella 5.5 calls for a specific evaluation.
View Article and Find Full Text PDFCrit Care Explor
July 2025
Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Virchow Klinikum, Berlin, Germany.
Importance: The effect of left ventricular (LV) mechanical unloading on right ventricular (RV) function in patients with cardiogenic shock (CS) remains poorly understood, yet may have significant implications for device weaning and patient outcomes.
Objectives: To investigate the short-term effects of LV unloading using a transaortic valve axial flow pump (Impella) on RV function and to assess its predictive value for successful device weaning in patients with CS.
Design: Retrospective analysis of CS patients who received Impella support between 2018 and 2021.
J Heart Lung Transplant
June 2025
Division of Cardiology, Department of Medicine, University of Chicago, Chicago, IL.
The Impella 5.5 (Abiomed, USA) is a catheter-based micro-axial flow pump that has emerged as a vital tool in managing patients with cardiogenic shock (CS). Delivering up to 5.
View Article and Find Full Text PDFMultimed Man Cardiothorac Surg
June 2025
Center for Surgery of the Aorta, Coronary and Peripheral Arteries, Meshalkin National Medical Research Center Ministry of Health of Russian Federation, Novosibirsk, Russian Federation
The rising number of people with heart failure is leading to a corresponding increase in heart failure-related deaths. End-of-life care for these patients involves supplementing standard treatments with therapies aimed at managing symptoms that don't respond to guideline-directed medical care. The INCOR, a lightweight (200 g), implantable, magnetically levitated axial flow pump (providing non-pulsatile flow), is designed for long-term left ventricular support.
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