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Following spinal cord injury (SCI), upper extremity (UE) weakness may impede one's ability to carry out activities of daily living (ADLs). Such a limitation drastically lowers a person's level of independence. Additionally, therapy and the field of assistive technology continue to place a strong premium on the restoration of UE motor function in patients with SCI. The main objective of this study was to assess the benefits of an UE myoelectric-powered wearable orthosis (MPWO) produced by MyoMo, Inc. (Boston, MA) on improving UE motor function in order to enhance ADLs and quality of life in individuals with subacute SCI. A 43-year-old man with subacute incomplete SCI (iSCI), American Spinal Injury Association (ASIA) Impairment Scale (AIS) C grade received 18 sessions (over a period of six weeks) of UE mobility therapy utilizing the MPWO. The MPWO was used to enhance active range of motion (AROM) of the hand and elbow, and associated muscle activations. After training with the MPWO, hand and elbow AROM and muscle activations were enhanced. These preliminary findings imply that UE-MPWO device-assisted rehabilitation may increase participants' UE activities, leading to improved function.Clinical Relevance- These preliminary findings from a person with iSCI in the subacute phase indicate that training with UE-MPWO assistive devices may enhance UE use during ADLs for people with muscle weakness but still having some residual voluntary muscle activation ability.
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http://dx.doi.org/10.1109/EMBC40787.2023.10340685 | DOI Listing |
Front Rehabil Sci
August 2025
Department of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Introduction: This study examines the effects of regular physical activity on upper extremity motor recovery during the late subacute and chronic phases of stroke.
Methods: Data were aggregated from 20 studies comprising 368 participants in control groups receiving usual care or general rehabilitation without specialized interventions. To isolate the impact of non-specific physical activity, studies involving robotics or task-specific therapies were excluded.
Front Bioeng Biotechnol
August 2025
Department of Orthopaedic, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.
Introduction: Traditional models for studying wound healing, including 2D cell cultures and animal models, present substantial limitations in mimicking human skin physiology. In this study, we present a three-dimensional wounded skin equivalent (3DWoundSE) composed of human cells as a physiologically relevant platform to investigate wound healing processes.
Methods: The model builds upon a previously established 3D skin equivalent (3DSE) and incorporates a reproducible partial-thickness dermal punch wound.
Front Neurol
August 2025
Department of Neurosurgery, Xingtai Ninth Hospital, Xingtai, China.
Introduction: The aim of this study was to evaluate the clinical outcomes of spinal cord stimulation (SCS) in patients with painful diabetic peripheral neuropathy (PDPN).
Materials And Methods: Ninety-two patients underwent permanent SCS implantation and completed a 6-month post-operative follow-up. The primary endpoint was patient amputation rate, and secondary endpoints included Quality of Life (QOL LC V2.
Front Neurol
August 2025
Department of Rehabilitation Medicine, Shaoguan First People's Hospital, Shaoguan, China.
Backgrounds: In clinical practice, many patients cannot undergo inpatient rehabilitation in hospitals for extended periods due to personal financial constraints, as well as China's health insurance policy. They are often forced to terminate their rehabilitation training during the prime recovery phase. This makes tele-rehabilitation-based, home-based rehabilitation particularly important.
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September 2025
School of Information and Communication Engineering, North University of China, Taiyuan, China.
Aims: Decoding the motor intention by electroencephalography to control external devices is an effective method of helping spinal cord injury (SCI) patients to regain motor function. Still, SCI patients have much lower accuracy in the decoding of motor intentions compared to healthy individuals, which severely hampers the clinical application. However, the underlying neural mechanisms are still unknown.
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