Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Aims: To investigate the dose-response association between physical activity and all-cause and cardiovascular mortality in adults with type 2 diabetes mellitus and the effects of replacing sedentary behavior with physical activity.
Methods: 4808 adults with type 2 diabetes mellitus were included in NHANES 2007-2018. Cox proportional hazards models were used to calculate hazard ratios and 95% confidence intervals. Isotemporal substitution analyses were further to determine the possible benefit of replacing sedentary time.
Results: During a median follow-up of 6.58 years, 902 deaths occurred, including 290 deaths from cardiovascular disease. Compared with the inactive group, the low-active and high-active groups were associated with declined risks of all-cause mortality [HRs (95% CIs) 0.64 (0.50, 0.83); 0.60 (0.50, 0.73), respectively] and cardiovascular mortality [0.50 (0.29, 0.88); 0.54 (0.39, 0.76)), respectively]. Dose-response analysis showed a significant U-shaped curve between physical activity and all-cause and cardiovascular mortality. Replacing 30 min/day of sedentary time with physical activity was substantially linked to a reduced risk of 8-32% mortality.
Conclusion: A high level of PA of 40.52 and 31.66 MET-h/week was respectively related to the lowest risk of all-cause and cardiovascular mortality. Replacing sedentary time with physical activity could benefit the type 2 diabetes mellitus population.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pcd.2023.11.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Airway obstruction and gender affect arterial stiffness in children with cystic fibrosis.
Turk J Pediatr
September 2025
Department of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.
Background: Vascular changes are observed in children with cystic fibrosis (cwCF), and gender-specific differences may impact arterial stiffness. We aimed to compare arterial stiffness and clinical parameters based on gender in cwCF and to determine the factors affecting arterial stiffness in cwCF.
Methods: Fifty-eight cwCF were included.
Association of problematic internet use with health-related daily habits in adolescents: evidence from a school-based survey.
Turk J Pediatr
September 2025
Department of Pediatrics, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Türkiye.
Background: With the development of technology, easier access to the internet and its excessive use have led to problematic internet use (PIU). The prevalence of PIU and its association with lifestyle behaviors in adolescents have become subjects of increasing academic interest. This study aimed to determine the prevalence of PIU among Turkish high school students and to investigate its association with sleep, physical activity and dietary habits.
View Article and Find Full Text PDF[Reflections derived from report: The Lancet commission on medicine, nazism, and the holocaust: historical evidence, implications for today, teaching for tomorrow].
Cuad Bioet
September 2025
Universidad Católica de Murcia. Observatorio de Bioética de la Universidad Católica de Valencia. Carlos Albors, 34. 46220 Picassent
Although, in principle, the Lancet article Commission on Medicine, Nazism, and the Holocaust, aims to provide medical students with a moral compass to guide the future of medical practice as a social retaining wall against anti-Semitism, it deals with the Holocaust not from a philosophical point of view, but from a pedagogical one, resorting to didactic strategies from a historiographical approach. What seemed to be a plea against the behaviour of the Nazi doctors' experiments becomes a justification of the positive law of the liberal democracies in use. However, what it ignores is of the utmost importance: that the majority of the regime's doctors were tried and sentenced for their iniquitous actions, and yet, in contemporary Western society, an even greater danger is very much present: techno-science, which, as it stands, can once again compromise the identity, dignity and very life of the human person.
View Article and Find Full Text PDFPerceived reward certainty in the assessment of delay discounting.
J Exp Anal Behav
September 2025
Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States of America.
Reward delays are often associated with reduced probability of reward, although standard assessments of delay discounting do not specify degree of reward certainty. Thus, the extent to which estimates of delay discounting are influenced by uncontrolled variance in perceived reward certainty remains unclear. Here we examine 370 participants who were randomly assigned to complete a delay discounting task when reward certainty was either unspecified (n=184) or specified as 100% (n = 186) in the task trials and task instructions.
View Article and Find Full Text PDFLong sequence temporal knowledge tracing for student performance prediction via integrating LSTM and informer.
PLoS One
September 2025
School of Electrical and Information Engineering, Hunan Institute of Technology, Hengyang, Hunan, China.
Knowledge tracing can reveal students' level of knowledge in relation to their learning performance. Recently, plenty of machine learning algorithms have been proposed to exploit to implement knowledge tracing and have achieved promising outcomes. However, most of the previous approaches were unable to cope with long sequence time-series prediction, which is more valuable than short sequence prediction that is extensively utilized in current knowledge-tracing studies.
View Article and Find Full Text PDF